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Take a look at our ISAC News and Information Page!
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International Society of Antimicrobial Chemotherapy (ISAC) News and Information Page
www.sciencedirect.com
January 27, 2026 at 10:25 PM
It is happening in the next few hours. See you soon~
Join us for a special ISAC session marking One Health Awareness Month! 🌍
Launching “One Health” Special Issue and exploring how human, animal & environmental health are all connected in the fight against AMR.

Register now us02web.zoom.us/webinar/regi...

@isacworld.bsky.social #OneHealth #AMR
January 14, 2026 at 5:01 AM
Join us for a special ISAC session marking One Health Awareness Month! 🌍
Launching “One Health” Special Issue and exploring how human, animal & environmental health are all connected in the fight against AMR.

Register now us02web.zoom.us/webinar/regi...

@isacworld.bsky.social #OneHealth #AMR
January 10, 2026 at 10:20 PM
💊 tet(X4) Resistance in Klebsiella| IJAA Vol.67 Issue 1 (In progress)
Global One Health dissemination of tet(X4) via mobile plasmids, often co-existing with carbapenem and colistin resistance, signals a serious public health risk.
📖 www.sciencedirect.com/science/arti...
@isacworld.bsky.social
Genome-wide insight into the evolution and global transmission of tigecycline resistant tet(X4)-carrying Klebsiella species across reservoirs
The emergence of plasmid mediated tet(X4) gene compromises the clinical utility of tigecycline and underscores growing concerns regarding its environm…
www.sciencedirect.com
December 30, 2025 at 4:16 PM
💊 Phage Depolymerases vs hvKP | IJAA Vol.67 Issue 1 (In progress)
TFP41 and TSP42 strip the K2 capsule of hypervirulent K. pneumoniae, enhance immune clearance, and deliver up to 100% survival in murine pneumonia models.
📖 www.sciencedirect.com/science/arti...
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Two Tail Protein-Derived Capsule Depolymerases From Phage vB_KpnS_GH-K1 are Effective Against Pneumonia Caused by K2 Serotype Klebsiella pneumoniae
Hypervirulent Klebsiella pneumoniae (hvKP) poses an escalating threat to public health and animal husbandry, underscoring the urgent need for novel an…
www.sciencedirect.com
December 23, 2025 at 11:11 AM
💊 Predicting AKI in Glycopeptide Therapy | IJAA Vol.67 Issue 1 (In progress)
An explainable XGBoost model predicts vancomycin- and teicoplanin-associated AKI, enabling early, personalized risk assessment.
📖 doi.org/10.1016/j.ij...
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Redirecting
doi.org
December 16, 2025 at 3:51 AM
💊 Prophage Activation & Antibiotics | IJAA Vol.67 Issue 1 (In progress)
A brief review of how antibiotics drive or inhibit prophage induction, influence toxin release and gene transfer, and guide safer therapy decisions.
📖 www.sciencedirect.com/science/arti...
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Antibiotic-mediated prophage activation: Mechanisms, consequences, and therapeutic implications
Prophages, as an integral part of bacterial genomes, play a pivotal role in regulating host virulence and shaping bacterial evolution. Exposure to ant…
www.sciencedirect.com
December 9, 2025 at 10:43 AM
🌍 Nanomedicine for Phage Therapy | IJAA Vol.67 Issue 1 (In progress)
A concise review of how nanoparticles, liposomes, hydrogels and nanofibers enhance phage stability, delivery and efficacy against MDR pathogens.
📖 www.sciencedirect.com/science/arti...
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Nanomedicine for phage therapy: Encapsulation strategies for enhanced antimicrobial efficacy
Antibiotic resistance is a growing global health crisis, driving the need for alternative antimicrobial strategies. Phage therapy has re-emerged as a …
www.sciencedirect.com
December 2, 2025 at 2:37 PM
🚀 IJAA Vol. 66 Issue 6 is out!
Highlights: global AMR burden, MRSA, One Health, AI strategies, and the Global Landscape of Phage Therapy.
📖 www.sciencedirect.com/journal/inte...
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International Journal of Antimicrobial Agents | Vol 66, Issue 6, December 2025 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
November 25, 2025 at 9:36 AM
🌍 Commercial Phage Therapy Prospects| IJAA Vol.66 Issue 6 (In progress)
Analysis reveals a surge in phage therapy patents & clinical trials, yet post-approval regulatory & economic hurdles remain for commercial success.
📖 www.sciencedirect.com/science/arti...
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The prospect of approved and commercially available phage therapeutics
As antibiotic resistance of bacterial pathogens spreads, interest in bacteriophage (phage) therapy has soared again in many countries. Currently, ther…
www.sciencedirect.com
November 18, 2025 at 11:58 AM
🌍 Global Landscape of Phage Therapy | IJAA Vol.66 Issue 6
An international survey uncovers clinicians’ perspectives on phage therapy, revealing growing optimism, diverse experiences, and global challenges in clinical adoption.
📖 www.sciencedirect.com/science/arti...
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Phage therapy: An international survey of attitudes and experiences amongst clinicians
Phage therapy is a promising tool to combat the global threat of antimicrobial resistance. Clinicians, as part of interdisciplinary teams, play an int…
www.sciencedirect.com
November 11, 2025 at 7:21 AM
🤖 AI Strategies to Combat AMR | IJAA Vol.66 Issue 5
Whole genome-based machine learning predicts AMR in nontyphoidal Salmonella, providing genomic insights to enhance AI-driven surveillance and precision control.
📖 www.sciencedirect.com/science/arti...
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Genomic insights into nontyphoidal Salmonella: Prediction of antimicrobial resistance with whole genome-based machine learning
Nontyphoidal Salmonella is a world-leading foodborne pathogen associated with an increased rate of antimicrobial resistance (AMR) and remains endemic …
www.sciencedirect.com
November 4, 2025 at 10:08 AM
🌏 Hot Topic | IJAA Vol.66 Issue 5
Survey finds 97% of Australian ID physicians would use phage therapy if safety standards are met, highlighting its promise against drug-resistant infections and priorities for clinical use.
📖 www.sciencedirect.com/science/arti...
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October 8, 2025 at 9:19 AM
🌍 IJAA Vol.66, Issue 5
Hot Topic: Phage therapy in Australia.
AMR highlights: WGS-based AMR prediction, polymyxin B synergy vs P. aeruginosa, CREC in China, Raman AI for MRSA/CRKP, CRKP in Portugal.
📖 www.sciencedirect.com/journal/inte...

#IJAA #AMR
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International Journal of Antimicrobial Agents | Vol 66, Issue 5, November 2025 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
October 3, 2025 at 6:07 AM
Explore the latest from IJAA (Vol. 66, Issue 4)!
🦠 Phage therapy: models & clinical use
🧬 Klebsiella resistance evolution
💊 Cefiderocol & β-lactamase detection
🔬 Serum lipids modulating S. aureus phage sensitivity
📈 Vancomycin dosing in the critically ill

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International Journal of Antimicrobial Agents | Vol 66, Issue 4, October 2025 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
September 5, 2025 at 5:15 AM
📢 New in IJAA Vol. 66, Issue 1!

🧬 AMR in the rumenofaecobiome
💊 Posaconazole in rare IFIs
🦠 IFN-λ in respiratory models
💉 Tigecycline modulates sepsis immunity
🌍 Global CRE resistance patterns
🧪 CRISPR assay for GES β-lactamase

📖 Read: www.sciencedirect.com/journal/inte...
International Journal of Antimicrobial Agents | Vol 66, Issue 1, July 2025 | ScienceDirect.com by Elsevier
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
July 15, 2025 at 4:49 AM
Check out the latest issue!

Dive into groundbreaking research on host-directed therapies, antimicrobial mechanism, multiomics informed mathematical model and the spread of antimicrobial-resistant pathogens

Read now:
www.sciencedirect.com/journal/inte...

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International Journal of Antimicrobial Agents | Vol 65, Issue 6, June 2025 | ScienceDirect.com by ElsevierScienceDirect
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
April 22, 2025 at 11:40 PM