Right now it's Usagi Yojimbo. Ever since I finished it in March I can't get it out of my head. Stan Sakai is a true master of cartooning. No panels, no bubbles of dialogue wasted concluding in fantastic pacing. An almost perfect comic book for all ages.

We also have books 2 and 3 of the new Lands Unknown series confirmed by Mignola himself.

New Mignola comics!
The Serpent in the Garden: Ed Grey and the Last Battle for England - Nov 27
Bowling with Corpses & Other Strange Tales from Lands Unknown - January
Frankenstein: New World - The Sea of Forever - Feb 5
Giant Robot Hellboy Returns - Mar 5