Ivan Bessonov
@ibessonov.bsky.social
Once a chemist, now a medical device nerd. Husband, dad, terrible weather enjoyer.
Tech cofounder at Efferon - extracorporeal treatment of sepsis.
Tech cofounder at Efferon - extracorporeal treatment of sepsis.
this is, probably, the most surprising point for me
turns out, these rogue endometrial cells are switching to anaerobic lactate metabolism JUST AS cancerous cells do
pmc.ncbi.nlm.nih.gov/articles/PMC...
turns out, these rogue endometrial cells are switching to anaerobic lactate metabolism JUST AS cancerous cells do
pmc.ncbi.nlm.nih.gov/articles/PMC...
June 14, 2025 at 5:44 PM
this is, probably, the most surprising point for me
turns out, these rogue endometrial cells are switching to anaerobic lactate metabolism JUST AS cancerous cells do
pmc.ncbi.nlm.nih.gov/articles/PMC...
turns out, these rogue endometrial cells are switching to anaerobic lactate metabolism JUST AS cancerous cells do
pmc.ncbi.nlm.nih.gov/articles/PMC...
i was under impression that Asgard archea only inhabit abyssal plains in deep oceanic floor
turns out, sweeping the coastal wetlands can yield HUNDREDS of their previously unknown genomes (China has it all)
and tell us new details about the emergence of Eukariotes
turns out, sweeping the coastal wetlands can yield HUNDREDS of their previously unknown genomes (China has it all)
and tell us new details about the emergence of Eukariotes
May 30, 2025 at 11:21 AM
i was under impression that Asgard archea only inhabit abyssal plains in deep oceanic floor
turns out, sweeping the coastal wetlands can yield HUNDREDS of their previously unknown genomes (China has it all)
and tell us new details about the emergence of Eukariotes
turns out, sweeping the coastal wetlands can yield HUNDREDS of their previously unknown genomes (China has it all)
and tell us new details about the emergence of Eukariotes
riding in a bad weather scores extra points of badassery, but riding in a nice weather just feels about right
May 19, 2025 at 8:26 PM
riding in a bad weather scores extra points of badassery, but riding in a nice weather just feels about right
i can attest - lack of grit and/or talent to withstand these “incentives” was a major factor behind my shift from academia into industry
talyarkoni.org/blog/2018/10...
talyarkoni.org/blog/2018/10...
May 2, 2025 at 11:02 AM
i can attest - lack of grit and/or talent to withstand these “incentives” was a major factor behind my shift from academia into industry
talyarkoni.org/blog/2018/10...
talyarkoni.org/blog/2018/10...
it was a great joy to visit Dubrovnik and attend the ICEOS conference on extracorporeal organ support
our stuff is now available across the Balkans and Adriatics
our stuff is now available across the Balkans and Adriatics
April 26, 2025 at 6:52 PM
it was a great joy to visit Dubrovnik and attend the ICEOS conference on extracorporeal organ support
our stuff is now available across the Balkans and Adriatics
our stuff is now available across the Balkans and Adriatics
i became a person who wakes up before 7:00 on vacation to rush a ghetto-gym
April 23, 2025 at 9:23 AM
i became a person who wakes up before 7:00 on vacation to rush a ghetto-gym
или вот вчера много про результаты этого опроса писали
«да, очень надо стоять у станка
нет, сам я этим заниматься не стану»
«да, очень надо стоять у станка
нет, сам я этим заниматься не стану»
April 14, 2025 at 2:49 PM
или вот вчера много про результаты этого опроса писали
«да, очень надо стоять у станка
нет, сам я этим заниматься не стану»
«да, очень надо стоять у станка
нет, сам я этим заниматься не стану»
мне кажется, это проявление общей закономерности, звучащей как «нашему обществу нужно затянуть пояса чтобы справиться с вызовами времени, но только пусть их затягивает кто-то другой»
вот например опрос о введении воинской повинности в Германии, старичьё поддерживает
www.ndr.de/ndrfragt/Umf...
вот например опрос о введении воинской повинности в Германии, старичьё поддерживает
www.ndr.de/ndrfragt/Umf...
April 14, 2025 at 2:48 PM
мне кажется, это проявление общей закономерности, звучащей как «нашему обществу нужно затянуть пояса чтобы справиться с вызовами времени, но только пусть их затягивает кто-то другой»
вот например опрос о введении воинской повинности в Германии, старичьё поддерживает
www.ndr.de/ndrfragt/Umf...
вот например опрос о введении воинской повинности в Германии, старичьё поддерживает
www.ndr.de/ndrfragt/Umf...
ok, so among 80 diverged genes the changes were introduced into… not even 20?
ok, that’s even funnier and gives a nice example how pronounced phenotypic differences can stem from changes in regulatory “non-coding” sequences
www.technologyreview.com/2025/04/08/1...
ok, that’s even funnier and gives a nice example how pronounced phenotypic differences can stem from changes in regulatory “non-coding” sequences
www.technologyreview.com/2025/04/08/1...
April 8, 2025 at 5:47 PM
ok, so among 80 diverged genes the changes were introduced into… not even 20?
ok, that’s even funnier and gives a nice example how pronounced phenotypic differences can stem from changes in regulatory “non-coding” sequences
www.technologyreview.com/2025/04/08/1...
ok, that’s even funnier and gives a nice example how pronounced phenotypic differences can stem from changes in regulatory “non-coding” sequences
www.technologyreview.com/2025/04/08/1...
20 targeted edits in 14 genes of modern-day gray wolf, a large and complex mammal, to make it resemble the long-extinct relative, is an impressive feat
but i have to admit, word “resurrection” feels wrong here
but i have to admit, word “resurrection” feels wrong here
April 8, 2025 at 6:29 AM
20 targeted edits in 14 genes of modern-day gray wolf, a large and complex mammal, to make it resemble the long-extinct relative, is an impressive feat
but i have to admit, word “resurrection” feels wrong here
but i have to admit, word “resurrection” feels wrong here
i believe, this also belongs to here
plastic waste goes to one container, paper - to another
that’s why forethoughtful package designer provided an easier way to detach paper from plastic
plastic waste goes to one container, paper - to another
that’s why forethoughtful package designer provided an easier way to detach paper from plastic
April 5, 2025 at 4:46 PM
i believe, this also belongs to here
plastic waste goes to one container, paper - to another
that’s why forethoughtful package designer provided an easier way to detach paper from plastic
plastic waste goes to one container, paper - to another
that’s why forethoughtful package designer provided an easier way to detach paper from plastic
this machine for peeling of asparagus’s thick skin is installed in our local grocery store
people around seem to really enjoy over-engineering things (and also processes)
people around seem to really enjoy over-engineering things (and also processes)
April 5, 2025 at 3:10 PM
this machine for peeling of asparagus’s thick skin is installed in our local grocery store
people around seem to really enjoy over-engineering things (and also processes)
people around seem to really enjoy over-engineering things (and also processes)
we’ve got sunny days with late sunsets
April 4, 2025 at 6:39 PM
we’ve got sunny days with late sunsets
i would have never guessed that my post-Soviet childhood could give me insights about contemporary American politics
April 3, 2025 at 5:45 PM
i would have never guessed that my post-Soviet childhood could give me insights about contemporary American politics
and there is another treasure hidden in this story:
ultramarine’s unique azure colour comes from the stable polysulphide anion-radical firmly trapped inside the polysilicate matrix
ultramarine’s unique azure colour comes from the stable polysulphide anion-radical firmly trapped inside the polysilicate matrix
April 3, 2025 at 1:03 PM
and there is another treasure hidden in this story:
ultramarine’s unique azure colour comes from the stable polysulphide anion-radical firmly trapped inside the polysilicate matrix
ultramarine’s unique azure colour comes from the stable polysulphide anion-radical firmly trapped inside the polysilicate matrix
www.astralcodexten.com/p/the-colors...
this is such a neat piece (and a relevant Calvin and Hobbes strip)
this is such a neat piece (and a relevant Calvin and Hobbes strip)
April 3, 2025 at 12:40 PM
www.astralcodexten.com/p/the-colors...
this is such a neat piece (and a relevant Calvin and Hobbes strip)
this is such a neat piece (and a relevant Calvin and Hobbes strip)
April 3, 2025 at 9:43 AM
то есть, существуют целые институты астробиологии и люди всерьёз эту тему изучают
а я думал, это чисто сказочное явление
а я думал, это чисто сказочное явление
April 3, 2025 at 8:23 AM
то есть, существуют целые институты астробиологии и люди всерьёз эту тему изучают
а я думал, это чисто сказочное явление
а я думал, это чисто сказочное явление
far to many books I’ve read seem to follow the pattern
1) a brilliant overview of currently accepted model of the world
2) weak points and internal contradictions of the model are wittily highlighted
3) an authors’ pet theory in hope to solve these riddles
Brian Greene, Gregory Clark, Nick Lane…
1) a brilliant overview of currently accepted model of the world
2) weak points and internal contradictions of the model are wittily highlighted
3) an authors’ pet theory in hope to solve these riddles
Brian Greene, Gregory Clark, Nick Lane…
March 31, 2025 at 6:59 AM
far to many books I’ve read seem to follow the pattern
1) a brilliant overview of currently accepted model of the world
2) weak points and internal contradictions of the model are wittily highlighted
3) an authors’ pet theory in hope to solve these riddles
Brian Greene, Gregory Clark, Nick Lane…
1) a brilliant overview of currently accepted model of the world
2) weak points and internal contradictions of the model are wittily highlighted
3) an authors’ pet theory in hope to solve these riddles
Brian Greene, Gregory Clark, Nick Lane…
“the collective noun for a group of geese on the ground is a gaggle;
when in flight, they are called a skein, a team, or a wedge;
when flying close together, they are called a plump.”
when in flight, they are called a skein, a team, or a wedge;
when flying close together, they are called a plump.”
March 24, 2025 at 7:40 AM
“the collective noun for a group of geese on the ground is a gaggle;
when in flight, they are called a skein, a team, or a wedge;
when flying close together, they are called a plump.”
when in flight, they are called a skein, a team, or a wedge;
when flying close together, they are called a plump.”
it took me painfully long to realise that it was Peter Bruegel who originated the Wimmelbuch concept
March 23, 2025 at 10:49 AM
it took me painfully long to realise that it was Peter Bruegel who originated the Wimmelbuch concept
yes, i had to be at the farthest point from home to puncture that tire
if only this brilliant podcast could last a few times longer
seriously though, it’s a great introduction into a currently run long-termed experiment on evolution of multicellularity
if only this brilliant podcast could last a few times longer
seriously though, it’s a great introduction into a currently run long-termed experiment on evolution of multicellularity
March 22, 2025 at 12:45 PM
yes, i had to be at the farthest point from home to puncture that tire
if only this brilliant podcast could last a few times longer
seriously though, it’s a great introduction into a currently run long-termed experiment on evolution of multicellularity
if only this brilliant podcast could last a few times longer
seriously though, it’s a great introduction into a currently run long-termed experiment on evolution of multicellularity
ripe jalapeños, garlic, fish sauce processed into bits and lactofermented for ~2 weeks (up to pH 3.9)
added a bunch of vinegar, sterilised and bottled
next time would do it with plums and habaneros
added a bunch of vinegar, sterilised and bottled
next time would do it with plums and habaneros
March 18, 2025 at 9:07 AM
ripe jalapeños, garlic, fish sauce processed into bits and lactofermented for ~2 weeks (up to pH 3.9)
added a bunch of vinegar, sterilised and bottled
next time would do it with plums and habaneros
added a bunch of vinegar, sterilised and bottled
next time would do it with plums and habaneros