Alex Hughes Lab
@hugheslabpenn.bsky.social
Lab-run account @ Penn Bioengineering. Studying development and tissues using micro-scale engineering, chemical biology, and microscopy. alexhugheslab.com
We used Hausdorff distance to compare 3D shapes in model:experiment in this paper:
advanced.onlinelibrary.wiley.com/doi/full/10....
Some spatial frequency approach might help you quantify the 'bumpiness' separate from the 'shape'.
Seems like @keenancrane.bsky.social would be helpful
advanced.onlinelibrary.wiley.com/doi/full/10....
Some spatial frequency approach might help you quantify the 'bumpiness' separate from the 'shape'.
Seems like @keenancrane.bsky.social would be helpful
Guiding Cell Network Assembly using Shape‐Morphing Hydrogels
Choreographed movement of cells and extracellular matrix (ECM) is a common, yet under-engineered tissue-building process. Shape-changing metamaterials (“kinomorphs”) made from precisely patterned cel...
advanced.onlinelibrary.wiley.com
May 28, 2025 at 11:02 PM
We used Hausdorff distance to compare 3D shapes in model:experiment in this paper:
advanced.onlinelibrary.wiley.com/doi/full/10....
Some spatial frequency approach might help you quantify the 'bumpiness' separate from the 'shape'.
Seems like @keenancrane.bsky.social would be helpful
advanced.onlinelibrary.wiley.com/doi/full/10....
Some spatial frequency approach might help you quantify the 'bumpiness' separate from the 'shape'.
Seems like @keenancrane.bsky.social would be helpful
Cool thread Rikki, the adhesion and motility correlation makes sense and neat to see the data collapse onto it. cancer invasion / emt would show negative corr right? Also wondering about when global dev rate is faster or slower, local self-organization has to match rate of events happening nearby
April 24, 2025 at 8:12 PM
Cool thread Rikki, the adhesion and motility correlation makes sense and neat to see the data collapse onto it. cancer invasion / emt would show negative corr right? Also wondering about when global dev rate is faster or slower, local self-organization has to match rate of events happening nearby