Very curious and excited to see the cool work of the Maniou lab! Congratulations Eirini the best are yet to come!

2. iPSC neuroepithelial models by @hpscenthusiast.bsky.social identifying a patient mutation in VANGL2 which diminishes apical constriction in this human model
www.biorxiv.org/content/10.1...

In this work we establish a platform for robust modelling of iPSC-derived neuropethelium. Using this, we characterise disease-associated phenotypes and show that a patient identified Vangl2 mutation disrupts apical constriction. Huge thanks to @emaniou.bsky.social @paolodecoppi.bsky.social