KHKV, MBBS
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hookonpath.bsky.social
KHKV, MBBS
@hookonpath.bsky.social
Associate Professor
Board-certified AP/CP, Dermatopathologist, Cytopathologist
Surgical Pathology enthusiast.
Knowledge Seeker.
Visualiser.
December 30, 2024 at 5:15 PM
This is a continuation of the case below: infant with scalp mass.
December 20, 2024 at 3:31 PM
Diagnosis: Acute B-cell lymphoblastic leukemia/lymphoma with a KMT2A (MLL) rearrangement, aka mixed-lineage leukemia. KMT2A is seen in 10% of ALL, particularly infant leukemia. Clinical relevance: KMT2A is an important prognostic marker with poor outcomes and resistance to standard therapies.
December 20, 2024 at 3:29 PM