Kenneth Hoehn
@hoehnlab.bsky.social
Assistant Professor at Dartmouth. Computational immunologist. B cell phylogenetics to study vaccinations, autoimmune diseases, and food allergies.
hoehnlab.org
hoehnlab.org
Pinned
TyCHE enables time-resolved lineage tracing of heterogeneously-evolving populations
Phylogenetic methods for cell lineage tracing have driven significant insights into organismal development, immune responses, and tumor evolution. While most methods estimate mutation trees, time-reso...
www.biorxiv.org
Excited to share my lab’s first preprint! We introduce TyCHE, which builds time-resolved lineage trees using sequences from populations evolving at drastically different rates. Examples include B cells, tumors, and some bacteria and viruses. (1/7) www.biorxiv.org/content/10.1...
Excited to share my lab’s first preprint! We introduce TyCHE, which builds time-resolved lineage trees using sequences from populations evolving at drastically different rates. Examples include B cells, tumors, and some bacteria and viruses. (1/7) www.biorxiv.org/content/10.1...
TyCHE enables time-resolved lineage tracing of heterogeneously-evolving populations
Phylogenetic methods for cell lineage tracing have driven significant insights into organismal development, immune responses, and tumor evolution. While most methods estimate mutation trees, time-reso...
www.biorxiv.org
October 23, 2025 at 5:24 PM
Excited to share my lab’s first preprint! We introduce TyCHE, which builds time-resolved lineage trees using sequences from populations evolving at drastically different rates. Examples include B cells, tumors, and some bacteria and viruses. (1/7) www.biorxiv.org/content/10.1...