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hms-bcmp.bsky.social
Harvard Med BCMP
@hms-bcmp.bsky.social
Department of Biological Chemistry and Molecular Pharmacology at HMS. Dedicated to elucidating and visualizing molecular mechanisms in biology and medicine.
Please join us for a BCMP seminar on Thursday, May 8 at 2pm by Jennifer Listgarten, Professor, Dept of Electrical Engineering and Computer Science, the Center for Computational Biology, and the Bioengineering program at UC Berkeley. @jlistgarten.bsky.social @ucberkeleyofficial.bsky.social
May 7, 2025 at 2:56 PM
Read all about Apoorva Baluapuri’s new work on Integrator (INT) in HMS News! @baluapuri.bsky.social @adelmanlab.bsky.social
tinyurl.com/y2fx22c2
What Happens When a Gene Quality-Control Mechanism Fails?
Study solves riddle of how mutations in Integrator complex relate to neurodegeneration, cancer
tinyurl.com
May 6, 2025 at 3:56 PM
Congrats to Stephen Buratowski and Johannes Walter for being elected to the Academy of Arts & Sciences! www.amacad.org/new-members-...
New Academy Members
Elected in 2025
www.amacad.org
April 25, 2025 at 5:46 PM
Reposted by Harvard Med BCMP
Published today in Cell Chemical Biology, our Cryo-EM structure of PP2A/B55α with IER5 and identification of IER5 structural homologues SERTADs using structural bioinformatics. Congratulations to Aster and @blacklowlab.bsky.social authors!

www.sciencedirect.com/science/arti...
Molecular mechanism of PP2A/B55α phosphatase inhibition by IER5
PP2A serine/threonine phosphatases are heterotrimeric complexes that execute many essential physiologic functions. These activities are modulated by a…
www.sciencedirect.com
April 9, 2025 at 3:29 PM
Exciting new work from Apoorva Baluapuri of the Adelman lab! @baluapuri.bsky.social
@adelmanlab.bsky.social
www.sciencedirect.com/science/arti...
April 18, 2025 at 8:44 PM
Please join us for a BCMP seminar on Thursday, April 3 at 2pm by Sebastian Klinge, Lenore C. Ford Professor, Dept of Biochemistry, Biophysics, Chemical Biology & Structural Biology, at The Rockefeller University. @rockefelleruniv.bsky.social
April 2, 2025 at 2:56 PM
Please join us for a BCMP seminar on Thursday, March 20 at 2pm by Natalia Jura, Professor, Dept of Cellular and Molecular Pharmacology and Cardiovascular Research Institute at UCSF. @uofcalifornia.bsky.social
March 19, 2025 at 4:29 PM
Please join us for a BCMP seminar on Thursday, March 6 at 2pm by Tanja Kortemme, Professor, Dept of Bioengineering & Therapeutic Sciences, Vice Dean of Research, UCSF School of Pharmacy. @uofcalifornia.bsky.social
March 5, 2025 at 4:11 PM
Reposted by Harvard Med BCMP
This was a great collaboration and culmination of a huge amount of work including our first attempt to join #teamtomo. @ruizhangmt.bsky.social expertly summarizes the highlights below:
Best way to start 2025! Thrilled to share our Nature paper about the structures of axonemal components from sperm flagella and from epithelial cilia of the oviduct and brain ventricles. Great collaboration with Tzviya Zeev-Ben-Mordehai and @alanbrownhms.bsky.social

www.nature.com/articles/s41...
January 2, 2025 at 3:09 PM
Please join us for a BCMP seminar on Thursday, February 13 at 2pm by Andrew Carter, Program Leader, MRC Laboratory of Molecular Biology. @mrclmb.bsky.social
February 12, 2025 at 4:32 PM
Please join us for a BCMP seminar on Thursday, January 30 at 2pm by Ed Boyden, Depts of Brain and Cognitive Sciences, Media Arts and Sciences, and Biological Engineering, Co-Director, MIT Center for Neurobiological Engineering Co-Director, K Lisa Yang Center for Bionics @mitofficial.bsky.social
January 29, 2025 at 6:24 PM
Join BCMP Faculty, Karen Adelman, at the Epigenetics in Development and Disease Meeting in Banff March 30-April 2.
February 19 is your last chance to get a $200 discount on the joint Epigenetics/Chromatin Architecture and Transcription Regulation meeting.

#KSEpigenetics25 #KSChromatin25 #epigenetics #humandevelopment #developmentalbiology #​​chromatin #chromatinarchitecture

youtu.be/zwUnqEdZduk
KSQA: Dr. Karen Adelman (Epigenetics)
YouTube video by KeystoneSymposia
youtu.be
January 28, 2025 at 10:08 PM
A new handle for understanding depression and the gut-brain connection? BCMP faculty Jon Clardy and colleagues report bacterial metabolism of environmental contaminant DEA drives cytokine IL-6 release. #microbiome #chemisky @pubs.acs.org
Drawing a Line From the Gut Microbiome to Inflammation and Depression
Study provides explanation for one bacterium’s link to mental health
tinyurl.com
January 28, 2025 at 8:21 PM
Can (and do) bugs make drugs? Learn about @hms-bcmp.bsky.social faculty Sloan Devlin and Jon Clardy, among other researchers, in the @harvardmagazine.bsky.social article exploring exciting work at @harvardmed.bsky.social decoding the chemistry of the microbiome! #microbiome #chemisky rb.gy/9hz8wu
Decoding the Chemistry of the Microbiome
rb.gy
January 22, 2025 at 8:13 PM
Please join us in person for a BCMP seminar on Thursday, January 16 at 2pm by Stephen Bell, Professor, Dept of Biology and HHMI Investigator. Please note the new location: Armenise Amphitheater Room 125. @mitofficial.bsky.social @hhmi.bsky.social
January 15, 2025 at 5:33 PM