HMMER
banner
hmmer.bsky.social
HMMER
@hmmer.bsky.social
Biosequence analysis using profile hidden Markov Models.
HMMER is managed by EMBL’s European Bioinformatics Institute (EMBL-EBI).

📣 We’re pleased to announce the release of jackhmmer.
It’s now available for use, and we’d greatly value any feedback as we continue to improve the tool.

www.ebi.ac.uk/Tools/hmmer/...
Give it a try and share your thoughts!

#bioinformatics #hmmer
July 11, 2025 at 7:09 AM
📣 We will be transitioning to a new website architecture on May 20, 2025.
We will not be running a parallel system, so you may have to make a few changes, especially if you are using the API.
May 7, 2025 at 2:19 PM
Service will be interrupted tomorrow, Thursday 29th, 0700 - 1100 BST owing to planned infrastructure changes.
March 31, 2025 at 10:23 AM
search services will be effected by this. https://x.com/emblebi/status/1091670896337698816
March 31, 2025 at 10:23 AM
The August release of @hmm3r is out!
It now includes @ChEMBL as a searchable sequence database 🔎
Try it now at https://www.ebi.ac.uk/Tools/hmmer/search/phmmer?seqdb=chembl
March 31, 2025 at 10:23 AM
Try the latest version of @hmm3r with the brand new @uniprot data. You can submit your search here 🔎
https://www.ebi.ac.uk/Tools/hmmer/search
https://x.com/uniprot/status/1019592114932416512
March 31, 2025 at 10:23 AM
Ever had too much data in your taxonomy tree?🌳 Try the new fisheye mode in the latest release of @hmm3r (“taxonomy” tab in your results) here https://www.ebi.ac.uk/Tools/hmmer/search/phmmer This visualisation uses this library https://github.com/ProteinsWebTeam/taxonomy-visualisation
March 31, 2025 at 10:23 AM
Try the latest version of @hmm3r with the new @uniprot data. You can submit your search here 🔎
https://www.ebi.ac.uk/Tools/hmmer/search/phmmer
https://x.com/uniprot/status/1010190457895374849
March 31, 2025 at 10:23 AM
🚨 @hmm3r website availability at risk on Saturday 9th June 🚨
Due to important system maintenance at the @emblebi, the Hmmer Website might become unavailable for some time tomorrow afternoon (UK time). 🚧
Sorry for the inconvenience.
March 31, 2025 at 10:23 AM
website now makes available @ensembl release 92 and @ensemblgenomes release 39. Try searching these databases now at https://www.ebi.ac.uk/Tools/hmmer/search/phmmer
March 31, 2025 at 10:23 AM
Try the latest version of @hmm3r with the new @uniprot data. You can submit your search here 🔎
https://www.ebi.ac.uk/Tools/hmmer/search/phmmer
https://x.com/uniprot/status/999322111020814337
March 31, 2025 at 10:22 AM
Are you experimenting with @BioSchemas? Have a look at the @hmm3r website. Pages are now annotated with structured data and result pages include current version of @BioSchemas annotations for protein, structures, and protein annotations.
https://www.ebi.ac.uk/Tools/hmmer/search/phmmer
March 31, 2025 at 10:22 AM
📢 With our newest release, you can now search the TreeFam database. Try it here https://www.ebi.ac.uk/Tools/hmmer/search/hmmscan and select the “TreeFam” option. http://www.treefam.org/
March 31, 2025 at 10:22 AM
You can try the latest version of @hmm3r with the new @uniprot data.
Give it a go at https://www.ebi.ac.uk/Tools/hmmer/search/phmmer
https://x.com/uniprot/status/991241316561489921
March 31, 2025 at 10:22 AM
The latest version of the @hmm3r website now contains the latest release of @ensemblgenomes, version 38. Try it now at https://www.ebi.ac.uk/Tools/hmmer/search/phmmer
March 31, 2025 at 10:22 AM
This data release is already included in the new release of the @hmm3r website. Search @uniprot release 2018_01 at https://www.ebi.ac.uk/Tools/hmmer/search/phmmer https://x.com/uniprot/status/958736502808285184
March 31, 2025 at 10:22 AM
📢 New version of the @hmm3r website available with MEROPS database version 12.
Try it now at https://www.ebi.ac.uk/Tools/hmmer/search/phmmer
March 31, 2025 at 10:22 AM
📢 New version of the @hmm3r website available with the new 2017_11 release from @uniprot (see https://x.com/uniprot/status/933374715615379456 …)
Try it now at https://www.ebi.ac.uk/Tools/hmmer/search/phmmer
March 31, 2025 at 10:22 AM
📢 New version of the @hmm3r website available with @CATHDatabase Gene3D version 16.0
Try it now at https://www.ebi.ac.uk/Tools/hmmer/search/hmmscan?hmmdb=gene3d
March 31, 2025 at 10:22 AM
📢 New version of @hmm3r website available with the brand new 2017_10 release from @uniprot. Try it now at https://www.ebi.ac.uk/Tools/hmmer/search/phmmer
March 31, 2025 at 10:22 AM
And the data is already available in the new version of the @hmm3r website! Search the latest @uniprot data now at https://www.ebi.ac.uk/Tools/hmmer/search/phmmer https://x.com/uniprot/status/913704907303243776
March 31, 2025 at 10:22 AM
🔐 Remember that the switch is happening today, during the next hours. If your script starts failing please check the URL you are using. https://x.com/hmm3r/status/910134236434305027
March 31, 2025 at 10:22 AM
📢 The new version of the @hmm3r website is out. It now includes @ensembl 90 and @ensemblgenomes 37. Try it at https://www.ebi.ac.uk/Tools/hmmer/search/phmmer
March 31, 2025 at 10:22 AM
Some servers stopped overnight, causing searches to be unavailable this morning. Everything should be back to normal now, sorry about that.
March 31, 2025 at 10:22 AM
In jackhmmer searches you now have the “unselect all” option for easier sequence selection across iterations. Try it https://www.ebi.ac.uk/Tools/hmmer/search/jackhmmer
March 31, 2025 at 10:22 AM