Hyung Jin Choi
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hjchoimd.bsky.social
Hyung Jin Choi
@hjchoimd.bsky.social
71 followers 90 following 15 posts
Neuroscience, Desire to Eat, Hunger, Hypothalamus, Homeostasis, Food Addiction, Obesity at Seoul National University
https://sites.google.com/snu.ac.kr/fnmrlabb
https://scholar.google.co.kr/citations?user=BVDyfWQAAAAJ&hl=ko
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hjchoimd.bsky.social
Hyung Jin Choi @hjchoimd.bsky.social · Jan 29
My research focuses on neural of eating and obesity with mouse, monkey and human.
Selected publications in Science, Neuron, Nature Communications, Science Advances and BioEssays: shorturl.at/DcUnm
CV: shorturl.at/UocTL
Lab Homepage: sites.google.com/snu.ac.kr/fn...
Google Scholar: shorturl.at/0scrl
Selected publications. Hyung Jin Choi
GLP-1 Increases Pre-ingestive Satiation via Hypothalamic Circuits in Mice and Humans. Science. 2024 Hypothalamic Neuronal Activation in Non-human Primates Drives Naturalistic Goal-directed Eating Beh...
shorturl.at
hjchoimd.bsky.social
Excited to share our new review on the cause and treatment of obesity based on personalized classification.
www.jomes.org/journal/view...
August 2, 2025 at 9:31 AM
hjchoimd.bsky.social
Our recent review on the neural mechanism of GLP-1 drug. Focusing on the role of hypothalamus and cognitive function.
e-dmj.org/journal/view...
May 16, 2025 at 10:11 AM
hjchoimd.bsky.social
I'm excited to share our recent review on lateral hypothalamus and eating: cell types, molecular identity, anatomy, temporal dynamics and functional roles.
www.nature.com/articles/s12...
Lateral hypothalamus and eating: cell types, molecular identity, anatomy, temporal dynamics and functional roles - Experimental & Molecular Medicine
The lateral hypothalamus (LH) is a key brain area involved in behaviors such as eating and drinking. This Review assesses how the LH controls eating, focusing on its complex organization. Researchers ...
www.nature.com
May 4, 2025 at 1:23 PM
hjchoimd.bsky.social
Awesome! This review provides a timely overview of the complexity of NTS. Molecular x Spatial Models. DBH+ neurons in the rostral NTS have been shown to be orexigenic [44, 47], while their caudal counterparts are anorexigenic [44]!!! Intersting!
April 16, 2025 at 3:47 PM
hjchoimd.bsky.social
Let's meet at Keystone. Neurobiology of Ingestive Behavior. I will present "Neural Circuits Integrating Hunger and Food Choices" study.
www.keystonesymposia.org/conferences/...
Neurobiology of Ingestive Behavior | Keystone Symposia
Join us at the Keystone Symposia on Neurobiology of Ingestive Behavior, April 2025, in Pacific Grove, with field leaders!
www.keystonesymposia.org
April 5, 2025 at 12:57 AM
hjchoimd.bsky.social
Let's meet tomorrow at Cell Symposia: Neurometabolism in health and disease. I will present
"Accumbal Neuropeptide Y Neurons Promote Reward Learning through Value Updating for Palatable Food" study!!
cell-symposia.com/neurometabol...
Home – Cell Symposium: Neurometabolism in Health and Disease
Cell Symposium: Neurometabolism in Health and Disease
cell-symposia.com
April 5, 2025 at 12:56 AM
hjchoimd.bsky.social
Excited to share our paper on Neuron. Chemogenetic activation of LH neurons in monkeys increased food motivation and naturalistic eating behaviors, mainly for palatable food. It's a translational follow-up of our rodent LH paper.
www.sciencedirect.com/science/arti...
Hypothalamic neuronal activation in non-human primates drives naturalistic goal-directed eating behavior
Maladaptive feeding behavior is the primary cause of modern obesity. While the causal influence of the lateral hypothalamic area (LHA) on eating behav…
www.sciencedirect.com
January 29, 2025 at 3:37 AM
hjchoimd.bsky.social
What are the psychological components that regulate our behavior? We published a "PROBLEMS & PARADIGMS" paper proposing a theoretical framework. Our lab is conducting experiments to discover the neural substrates for each component. I hope you enjoy it!
onlinelibrary.wiley.com/doi/10.1002/...
A unified theoretical framework underlying the regulation of motivated behavior
This article suggests psychophysiological components to regulate behavior. (1) “need”, an alarm regarding predicted deficiency. (2) “motivation”, a driver initiates behavior. (3) “pleasure”, a lesson...
onlinelibrary.wiley.com
January 29, 2025 at 3:35 AM
hjchoimd.bsky.social
HAPPY to share our new paper! Are there specific neurons for food need (hunger) and food motivation (appetite)? Computational modeling and neural activity recording dissociated these two neurons.
www.science.org/doi/10.1126/...
A normative framework dissociates need and motivation in hypothalamic neurons
Experimental and computational methods elucidate the neural substrates of need and motivation in hypothalamic neurons.
www.science.org
January 29, 2025 at 3:34 AM
hjchoimd.bsky.social
Excite to share our paper on Science. GLP-1 increases preingestive satiation via hypothalamic circuits in mice and humans
www.science.org/doi/10.1126/...
GLP-1 increases preingestive satiation via hypothalamic circuits in mice and humans
Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) are effective antiobesity drugs. However, the precise central mechanisms of GLP-1RAs remain elusive. We administered GLP-1RAs to patients w...
www.science.org
January 29, 2025 at 3:29 AM
hjchoimd.bsky.social
My research focuses on neural of eating and obesity with mouse, monkey and human.
Selected publications in Science, Neuron, Nature Communications, Science Advances and BioEssays: shorturl.at/DcUnm
CV: shorturl.at/UocTL
Lab Homepage: sites.google.com/snu.ac.kr/fn...
Google Scholar: shorturl.at/0scrl
Selected publications. Hyung Jin Choi
GLP-1 Increases Pre-ingestive Satiation via Hypothalamic Circuits in Mice and Humans. Science. 2024 Hypothalamic Neuronal Activation in Non-human Primates Drives Naturalistic Goal-directed Eating Beh...
shorturl.at
January 29, 2025 at 3:03 AM