Hirabayashi Lab - UTokyo
@hirabayashi-lab.bsky.social
After 6 years of careful experiments, we’re excited to share our latest manuscript on the identification and function of the PDZD8–FKBP8 protein complex! We now have convincing evidence that structural regulation of mitochondria via ER–mitochondria tethering proteins is real.
rdcu.be/eihrF
rdcu.be/eihrF
Mitochondrial complexity is regulated at ER-mitochondria contact sites via PDZD8-FKBP8 tethering
Nature Communications - How PDZD8 acted in Mitochondria-ER contact formation was unclear. Here, the authors show that binding to mitochondrial FKBP8 slows PDZD8’s rapid motion, enhancing...
rdcu.be
April 18, 2025 at 11:31 AM
After 6 years of careful experiments, we’re excited to share our latest manuscript on the identification and function of the PDZD8–FKBP8 protein complex! We now have convincing evidence that structural regulation of mitochondria via ER–mitochondria tethering proteins is real.
rdcu.be/eihrF
rdcu.be/eihrF