Helen Lin
helenyslin.bsky.social
Helen Lin
@helenyslin.bsky.social
Statistical geneticist and PhD student @ Baylor College of Medicine
Reposted by Helen Lin
📃 I am excited to share our @naturegenet.bsky.social review paper on the state of psychiatric genetics in Latin America, put forth by the Latin American Genomics Consortium (LAGC)! 🎉

www.nature.com/articles/s41...
Psychiatric genetics in the diverse landscape of Latin American populations - Nature Genetics
Latin America and the Caribbean remain largely underrepresented in psychiatric genetics research. This Review highlights the need for more research in these populations to advance genetic insights and...
www.nature.com
April 2, 2025 at 3:24 PM
Reposted by Helen Lin
www.biorxiv.org/content/10.1...
📄 New preprint alert! 📄
@helenyslin.bsky.social benchmarked polygenic scores (PGS) using genotyping arrays vs whole-genome sequencing (WGS) across traits & populations in @AllofUsResearch. What’s the best approach? The answer is… it depends! 🧵⬇️
Differential performance of polygenic prediction across traits and populations depending on genotype discovery approach
Polygenic scores (PGS) are widely used for estimating genetic predisposition to complex traits by aggregating the effects of common variants into a single measure. They hold promise in identifying ind...
www.biorxiv.org
March 20, 2025 at 2:53 PM
Reposted by Helen Lin
Differential performance of polygenic prediction across traits and populations depending on genotype discovery approach https://www.biorxiv.org/content/10.1101/2025.03.18.644029v1
March 19, 2025 at 6:32 AM