Helene Kretzmer
@helenekretzmer.bsky.social
Professor for Computational Genomics at Hasso Plattner Institute | MPI Molgen | Epigenetics | Cancer | Single Cell | Machine Learning
A big thank you to the whole team, including @marasteiger.bsky.social , Alena van Bömmel, Björn Brändl, and Franzef Müller, as well as all co-authors and collaborators!
Read the full paper here: www.nature.com/articles/s41...
Read the full paper here: www.nature.com/articles/s41...
Rapid brain tumor classification from sparse epigenomic data - Nature Medicine
MethyLYZR, an epigenetic classifier of brain tumors, provides clinically relevant cancer classification results within 15 min of sequencing, with potential applications for neurosurgical intraoperativ...
www.nature.com
March 2, 2025 at 4:01 PM
A big thank you to the whole team, including @marasteiger.bsky.social , Alena van Bömmel, Björn Brändl, and Franzef Müller, as well as all co-authors and collaborators!
Read the full paper here: www.nature.com/articles/s41...
Read the full paper here: www.nature.com/articles/s41...
This work was a collaborative effort between MPIMG, UKSH, FLI, and many other institutions, across areas of expertise in neuropathology, neuro-oncology, and computational biology.
March 2, 2025 at 4:01 PM
This work was a collaborative effort between MPIMG, UKSH, FLI, and many other institutions, across areas of expertise in neuropathology, neuro-oncology, and computational biology.
By leveraging Oxford Nanopore sequencing and a flexible Naïve Bayes classifier, we make classification feasible within the critical surgical timeframe, helping neurosurgeons adapt their strategy based on the tumor’s molecular profile.
March 2, 2025 at 4:01 PM
By leveraging Oxford Nanopore sequencing and a flexible Naïve Bayes classifier, we make classification feasible within the critical surgical timeframe, helping neurosurgeons adapt their strategy based on the tumor’s molecular profile.
We developed MethyLYZR, a machine learning framework that enables live tumor classification within 15 minutes of sequencing—bringing molecular diagnostics into the operating room.
March 2, 2025 at 4:01 PM
We developed MethyLYZR, a machine learning framework that enables live tumor classification within 15 minutes of sequencing—bringing molecular diagnostics into the operating room.