Heidi Jacobs
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heidijacobslab.bsky.social
Heidi Jacobs
@heidijacobslab.bsky.social
Associate Prof @MGH @HarvardMed @MaastrichtUni | Locus coeruleus & other neuromodulators in early detection and prevention of Alzheimer’s disease | 7T MRI, PET
Reposted by Heidi Jacobs
#ThisWeekInNPP

Early life stress profoundly impacts the 🧠 & can result in negative affective behaviors well into adulthood

Here, maternal separation stress produced dysregulated noradrenergic activity in the locus coeruleus (LC) across the lifespan, disrupting LC regulation of coping strategies
Maternal separation disrupts noradrenergic control of adult coping behaviors - Neuropsychopharmacology
Neuropsychopharmacology - Maternal separation disrupts noradrenergic control of adult coping behaviors
www.nature.com
September 9, 2025 at 5:08 PM