@heenaa02.bsky.social
6/ 🙏 Huge thanks to the amazing collaborators and co-authors who made this work possible!
🧑🔬 Basile Leduque, Leandro Quadrana, Keith Slotkin, Alexandros Bousios (@abousios.bsky.social) & Hans-wilhelm Nuetzmann
🧑🔬 Basile Leduque, Leandro Quadrana, Keith Slotkin, Alexandros Bousios (@abousios.bsky.social) & Hans-wilhelm Nuetzmann
July 22, 2025 at 1:25 PM
6/ 🙏 Huge thanks to the amazing collaborators and co-authors who made this work possible!
🧑🔬 Basile Leduque, Leandro Quadrana, Keith Slotkin, Alexandros Bousios (@abousios.bsky.social) & Hans-wilhelm Nuetzmann
🧑🔬 Basile Leduque, Leandro Quadrana, Keith Slotkin, Alexandros Bousios (@abousios.bsky.social) & Hans-wilhelm Nuetzmann
5/ 💻 Surprise package! We developed a custom pipeline, deNOVOEnrich, to profile somatic TE insertions from TEd-seq short-read data.
Using split-read mapping, we pinpoint new somatic insertions at base-pair resolution 🧬🔍
Check it out: github.com/hAmbreen02/d...
Using split-read mapping, we pinpoint new somatic insertions at base-pair resolution 🧬🔍
Check it out: github.com/hAmbreen02/d...
GitHub - hAmbreen02/deNOVOEnrich: Identification of de novo transposon insertion sites from targeted sequencing data
Identification of de novo transposon insertion sites from targeted sequencing data - hAmbreen02/deNOVOEnrich
github.com
July 22, 2025 at 1:21 PM
5/ 💻 Surprise package! We developed a custom pipeline, deNOVOEnrich, to profile somatic TE insertions from TEd-seq short-read data.
Using split-read mapping, we pinpoint new somatic insertions at base-pair resolution 🧬🔍
Check it out: github.com/hAmbreen02/d...
Using split-read mapping, we pinpoint new somatic insertions at base-pair resolution 🧬🔍
Check it out: github.com/hAmbreen02/d...
4/ 🔥 Somatic insertion hotspots of the EVADE transposon are enriched at environmentally responsive genes 🌄 - including Resistance gene and biosynthetic gene clusters.
Is stress guiding TE activity, or are TEs tuning stress responses?
Somatic genome plasticity 🧬
Is stress guiding TE activity, or are TEs tuning stress responses?
Somatic genome plasticity 🧬
July 22, 2025 at 1:21 PM
4/ 🔥 Somatic insertion hotspots of the EVADE transposon are enriched at environmentally responsive genes 🌄 - including Resistance gene and biosynthetic gene clusters.
Is stress guiding TE activity, or are TEs tuning stress responses?
Somatic genome plasticity 🧬
Is stress guiding TE activity, or are TEs tuning stress responses?
Somatic genome plasticity 🧬
3/ 🧬 Our work shows somatic TE activity in Arabidopsis is non‑random and family‑specific. Different TE families prefer distinct genomic niches - is it driven by underlying epigenetic code, or are they avoiding conflict in a shared genome ecosystem? 🤔
July 22, 2025 at 1:20 PM
3/ 🧬 Our work shows somatic TE activity in Arabidopsis is non‑random and family‑specific. Different TE families prefer distinct genomic niches - is it driven by underlying epigenetic code, or are they avoiding conflict in a shared genome ecosystem? 🤔
2/ Combining distinct experimental conditions, we traced a roadmap of expected TE movement in somatic cells 🌿, capturing ~200K new TE insertions across multiple families in the process.
July 22, 2025 at 1:19 PM
2/ Combining distinct experimental conditions, we traced a roadmap of expected TE movement in somatic cells 🌿, capturing ~200K new TE insertions across multiple families in the process.