HEADSpAcE Data Centre
LightNews LightNews
headspacestudy.bsky.social
HEADSpAcE Data Centre
@headspacestudy.bsky.social
29 followers 140 following 13 posts
Head and Neck Cancer Epidemiology and Genomic Studies on Prognosis and Survival - Large repository containing well-annotated clinical and exposure data from thousands of patients with HNC and controls from collaborative studies led by IARC/WHO.
Posts Replies Media Videos
headspacestudy.bsky.social
also, why is it revolutionizing clinical practice?
February 14, 2025 at 8:02 AM
headspacestudy.bsky.social
📚 Access the full study and FAQ:
IARC Handbooks of Cancer Prevention - Volume 20A
publications.iarc.who.int/638
IARC Publications Website - Reduction or Cessation of Alcoholic Beverage Consumption
publications.iarc.who.int
February 7, 2025 at 4:34 PM
headspacestudy.bsky.social
In 2024, a Working Group of IARC reviewed scientific evidence on the effects of reducing or stopping alcohol consumption versus continuous consumption in relation to the risk of cancers of the oral cavity, pharynx, larynx, esophagus, colorectal, liver and breast:
It's important to know that there are three well-established processes of carcinogenesis initiated by alcohol consumption*: Genotoxicity Acetaldehyde can accumulate in the upper air-digestive tract (head, neck and esophagus) and colon, increasing the risk of cell damage and carcinogenic mutations. Permeability and intestinal biota Acetaldehyde accumulation alters the enteral microbiome, which increases intestinal permeability and microbial translocation (which is when bacteria from the gut move to other parts of the body), potentially leading to inflammation and carcinogenic risks. DNA Damage Alcohol consumption is associated with direct damage to cell DNA, causing chromosomal aberrations, the appearance of micronuclei and DNA adducts, which can initiate the process of tumor formation. The good news is that there is evidence that these processes can be reversed by stopping or reducing alcohol consumption! By stopping drinking, the body has a chance to repair this damage. Compared to continued consumption, reducing or stopping alcohol consumption reduces the incidence of some cancers: oral cavity and esophagus: strong evidence* larynx, breast and colorectal: limited evidence*
February 7, 2025 at 4:34 PM
headspacestudy.bsky.social
Learn more on our website: headspace.iarc.who.int
HEADSpace: Home
headspace.iarc.who.int
November 29, 2024 at 4:57 PM
headspacestudy.bsky.social
📌 investigate tobacco exposure and tobacco-related health outcomes

[4/4]
November 29, 2024 at 4:57 PM
headspacestudy.bsky.social
📌 to research the disproportionate burden of head and neck cancers in low- and middle-income countries, conducting research and building partnerships in these regions;

[3/4]
November 29, 2024 at 4:57 PM
headspacestudy.bsky.social
📌 to inform strategies and interventions for cancer prevention and early detection and to improve cancer outcomes;

[2/4]
November 29, 2024 at 4:57 PM