A huge congratulations to Laurel Hiatt on their first first-author publication from their PhD!! And thank you to all our wonderful coauthors for making this happen.

Credit to Laurel Hiatt for driving this, @vincerubinetti.bsky.social for beautiful new website design, and Akshay Avvaru for data vis.
Thanks to the continued support of Ben Weisburd @egor-dolzhenko.bsky.social @heidirehm.bsky.social @aaronquinlan.bsky.social.
It's a pleasure working with you all!

Thanks for doing this, @tamargurmdphd.bsky.social ! Following

Algorithmically, I'd say some error correction may be needed, especially for long alleles and high GC repeats. It uses local SNVs, so that might be more challenging and result in read phasing errors.
This is a key obstacle: github.com/PacificBiosc... (see paragraph 3)

Unfortunately, no. It's tuned to HiFi read specs.

Huge congratulations to Egor Dolzhenko, Adam English, and everyone else involved. @aaronquinlan.bsky.social @meberle.bsky.social @sedlazeck.bsky.social @pacbio.bsky.social

TRGT also reports methylation. Here’s a nice analysis of the FMR1 Fragile X locus.

TRGT reports full sequence alleles, including repeat interruptions and motif diversity. We found some fascinating motif heterogeneity at the RFC1 CANVAS locus in HPRC.

Thanks! I also found this handy list: docs.google.com/spreadsheets...

Is this some emoji #hashtag magic?