Dr. Hardik Patel 🩺💉
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hardik4u24.bsky.social
Dr. Hardik Patel 🩺💉
@hardik4u24.bsky.social
Consultant Nephrologist 🫘 | Manipal Goa 🩺 Founder @BuddingNephrologist 🌱IND | Internist | Cricket 🏏 & Sachin Fan | RF 🎾 Fan | Lifelong Learner 📚
🥤#KidneyStone prevention — diet that protects your #kidneys 👇

🔗 doi.org/10.1136/post...

#Nephrology #Urology
October 16, 2025 at 3:49 PM
🔍Proteinuria in monoclonal gammopathy? Don’t miss the diagnostic clues!

🚰uAPR < 40%? Think tubular
🧪uAPR > 40%? Glomerular path ahead

From cast nephropathy to MGRS, biopsy is 🔑

📉LC ≤10%= cast nephropathy
📊LC >10%= #LCPT

🧬 #MGRS = Biopsy it

🔗 doi.org/10.1016/j.lp...

#NephSky #MGRS #MM #Medsky
August 2, 2025 at 4:13 PM
📉 Why are infections so common—and deadly—in people with chronic kidney disease?

🧠 SIDKD (Secondary Immune Deficiency of Kidney Disease) affects gut health, immune cells, metabolism & more.

This visual breaks it down beautifully 👇
🔗 doi.org/10.1097/IMNA... 🆕

🧬 Nephrologists, time to zoom in!
June 17, 2025 at 6:31 PM
🚨NEW Weapons vs #MDR bugs!

💉Explore 3️⃣ hot β-lactam/β-lactamase inhibitor combos:

🦠 Cefepime/enmetazobactam
🦠 Aztreonam/avibactam
🦠 Sulbactam/durlobactam

⚖️💧Renal dose adjustments? Covered👇

🔗 doi.org/10.3390/path... 🆕

#Nephrology #MedTwitter #ICU #ID #Antibiotics #IM
June 16, 2025 at 5:22 PM
💊💓HFrEF management is evolving!
Why wait months to optimize therapy?

👇Compare ESC 2021 vs McMurray/Packer 2021 strategies

💥 SGLT2i | GLP-1RA | Finerenone

Game-changers in 🫀, 🫘 & 🧠

🔗 doi.org/10.3390/jcm1...

#Nephrology #Cardiology #MedEd #SGLT2i #HeartFailure #CKD #IM #MedSky
June 16, 2025 at 5:20 PM
🥩🫘#HRS-AKI is more pre-renal than pre-renal AKI!🤯

Check out this mind-bending FENa table in cirrhosis-related AKI from a must-read #ICU review

🔑note: FENa is helpful—but don’t overtrust it alone!

🔗 doi.org/10.1177/0885... 🆕

#Nephrology #MedEd #AKI #Hepatology #Cirrhosis #NephSky #Hepatorenal
June 15, 2025 at 12:56 PM
🚨#SGLT2 inhibitors in cirrhosis? Where #Nephrology meets #Hepatology

🧪11/11:↓ ascites (💧less taps)
📉7/9: slowed progression (fewer decompensations)
⚠️AKI/hypotension in refractory cases—balance matters!

Dual win:Natriuresis + anti-inflammatory

🔗 doi.org/10.3390/ijms...
June 11, 2025 at 2:14 AM
🎛️Hemoadsorption in septic shock? Not so fast ❌

🚫 Immune meddling, 🎯 non‑selective action, 📉no survival edge &⚠️ potential harm

🔥 Massimo et al. editorial a must‑read for ICU & nephro teams

🔗 doi.org/10.1007/s001... 🆕

#Nephrology #ICU #Sepsis #AKI #CriticalCare #NephSky
June 5, 2025 at 4:54 PM
🚨Peripheral Artery Disease🦵 is up to 6x more common in CKD 🫘

❤️‍🔥Vascular calcification, inflammation & CKD-MBD🦴 fuel the fire 🔥

📉Don’t miss early signs—ankle-brachial index can help!

🔗https://doi.org/10.1093/ckj/sfaf089 @ckj-era.bsky.social review

#MedSky #MedEd #CKD #PAD #Nephrology #NephSky
June 4, 2025 at 3:00 PM
🦸‍♂️🦸‍♀️ Meet the Dynamic Duo in HFpEF/HFrEF!

SGLT2 inhibitors🟰Robin
Finerenone🟰Batman

Together they battle heart failure💔 with preserved/mid-range EF!

🔗 doi.org/10.36660/abc...

#NephSky #CardioRenal #HFpEF #SGLT2i #Finerenone #HeartFailure #MedSky #InternalMedicine
June 1, 2025 at 4:17 PM
🧬🔬Renal biopsy says amyloidosis… what next?

This brilliant IHC-based algorithm 🔁 guides you through AL, AA, & rare amyloid types—don’t miss that dual diagnosis!

🔗 doi.org/10.1159/0005... 🆕

#RenalPath #Amyloidosis #Nephrology #MedSky #BlueSky
May 30, 2025 at 11:51 AM
🫀Heart Failure in CKD🫘 isn’t just about fluid overload — and its Rampant in CKD 🔥-it’s a perfect storm of:

🧬Neurohormones
🦠Inflammation
🧪Uremic toxins
🧱Fibrosis
💣Metabolic chaos

🔗 doi.org/10.1161/CIRC...

#Nephrology #CRS #HF #HeartFailure #CKD #FOAMed #MedEd #IM #NephSky #MedSky
May 25, 2025 at 1:15 PM
🤔Ever seen IgG3 act this wild in the kidney?🫘

🔬PGNMID = mysterious monoclonal Ig with renal-limited fury

🧩Pathophys still unclear but beautifully illustrated here👇

📖Bridoux et al @ndt-era.bsky.social

🔗 doi.org/10.1093/ndt/...

#Nephrology #MGRS #PGNMID #MedTwitter #RenalPath #NephTwitter
May 16, 2025 at 9:07 AM
🚀Adrenal Incidentalomas Demystified

🥴Stumbled upon an adrenal mass ? Here’s your roadmap🚏

👉🏻Workup algorithm—from benign to suspicious 🦀what’s next?

⭐️A must-know for #Nephrology #Endocrinology #Urology 👩‍⚕️

🔗 doi.org/10.1097/JU.0...

#Incidentaloma #FOAMed #MedSky
#NephSky
April 27, 2025 at 5:41 AM
💉Immune checkpoint inhibitors: 🦸‍♂️heroes in cancer🦀, 🦹‍♂️villains for kidneys 🫘?

#ICI-AKI can hit both

Glomeruli (C3GN, MCD, vasculitis)
&
Tubulointerstitium (ATIN, ATN, tubulitis)

📖 doi.org/10.34067/KID... 🆕
@asnpublications.bsky.social K360

#Onconephrology #Nephrology #AKI #NephSky #NephPearls
April 26, 2025 at 9:24 AM
🧰New tools for early ICI-AKI detection!

💧Urine, 🩸 serum, and 📸 imaging markers are changing the game.

Protect kidneys 🫘 , save lives!🌱

🔗 doi.org/10.34067/KID...
@asnpublications.bsky.social K360
@sabinekaram.bsky.social et al

#Nephrology #OncoNephrology #AKI #NephSky #MedSky
#NephPearls
April 26, 2025 at 9:17 AM
🦀🦴Treatment of Cancer-Associated Hypercalcemia

➡️Start with IV fluids
➡️Then hit osteoclasts with #Bisphosphonates or #Denosumab

But remember, real control = treating the malignancy

🔗 www.nejm.org/doi/full/10....

#Hypercalcemia #Malignancy #OncoNephrology #Nephrology #IM #Oncology #MedSky #NephSky
March 30, 2025 at 3:09 PM
The CKD-Gut-Immune Axis: A Vicious Cycle 🫘

Uremic toxins → Gut dysbiosis → Inflammation → Immune dysregulation → CKD progression.

Can probiotics break the cycle?

📖 dx.doi.org/10.5527/wjn.... 2025 🆕

#Probiotics #Nephrology #CKD #GutHealth #Uremia #MedSky #NephSky
March 30, 2025 at 3:05 PM
#Leptospirosis & the #Kidney: A Deadly Duo🦠🫘

Lepto= non-oliguric #AKI→ ATN→ #CKD by blocking Na-K ATPase & inducing vasopressin resistance! Persistent inflammation= fibrosis & kidney failure.

🔗 doi.org/10.1007/s150... 🆕 2025

#Nephrology #InfectiousDiseases #InternalMedicine #MedSky #NephSky
March 22, 2025 at 3:46 AM
💡Pregnancy after transplant? 🤰🫘🫁🫀
What you need to know!

🔹Pre-pregnancy guidance
🔹Organ-specific outcomes
🔹Risks & expert recommendations

📖 doi.org/10.1097/TP.0... 🆕

@gonikatz.bsky.social @ttsorg.bsky.social (2025)

#TransplantNephrology #Pregnancy #Nephrology #MedTwitter #Transplantation
March 15, 2025 at 10:13 AM
⚠️Sterile Peritonitis in PD: Think Beyond Infection 🦠

🔍Not always infection!

A broad differential—drugs, malignancy, retrograde menstruation & more! 🏥💡

Freitas et al
🔗https://doi.org/10.1177/089686080502500207

#Nephrology #PeritonealDialysis #PD #MedEd #FOAMed #Dialysis #NephSky #MedSky
March 15, 2025 at 8:11 AM
🚨Endocrine Hypertension: More Than Just BP🚨

From resistant HTN to adrenal tumors—when should you suspect & how do you approach? 📊🔎

📖Borozan et al., Current Hypertension Reports (2025)
🔗 doi.org/10.1007/s119... 🆕

#Hypertension #Endocrinology #Nephrology #NephSky #MedSky
March 11, 2025 at 4:57 PM
🚰🔄Vesicoureteral Reflux (VUR): A Silent Threat to Kidneys🫘

From mild reflux to severe tortuosity—grading VUR is key📊

Know when & how to investigate🔍
@diseaseprimers.bsky.social

📖 doi.org/10.1038/s415... (2024-Primer)

#Nephrology #PedsNephro #VUR #UTI #MedEd #FOAMed #NephSky #MedSky
March 9, 2025 at 7:20 AM
Antiphospholipid Syndrome (APS): The Silent Thrombophilia

From molecular pathogenesis to devastating thrombotic complications—#APS is a ticking time bomb! ⏳🧬

📖 APS review: doi.org/10.3390/jcm1... (2025)

#Nephrology #Thrombosis #Lupus #MedTwitter #Rheumatology #Autoimmune
March 6, 2025 at 3:15 PM
🚨ECMO & AKI: A Deadly Combo🚨

Non-pulsatile flow & venous congestion—ECMO risks renal hypoperfusion, leading to AKI🫀🫘

Can we prevent it? Dive into this review👇

📖AKI in ECMO: Research Progress
🔗https://doi.org/10.1007/s10157-024-02559-7

#Nephrology #ECMO #AKI #CriticalCare #Cardiology #ICU
March 3, 2025 at 11:53 AM