@hannasimpson.bsky.social
That's amazing, would you mind sharing the link? I'm part of coeliac disease research team so maybe we can share some research insights?
December 13, 2024 at 5:14 PM
That's amazing, would you mind sharing the link? I'm part of coeliac disease research team so maybe we can share some research insights?
Is celiac disease also your field of research by the way?
December 13, 2024 at 1:08 PM
Is celiac disease also your field of research by the way?
Exactly! And super interesting questions, we're currently diving into these ideas. If you're interested, we have pre-print exploring gut microbiome in CeD patients that I could share?
December 13, 2024 at 12:09 PM
Exactly! And super interesting questions, we're currently diving into these ideas. If you're interested, we have pre-print exploring gut microbiome in CeD patients that I could share?
Certain bacteria can contribute to the partial metabolism and production of more immunogenic peptides that can better cross the epithelial barrier. Once crossed, the peptides undergo further processing, particularly demadidation, which confers high binding afinity to HLA-DQ2/8.
December 12, 2024 at 2:42 PM
Certain bacteria can contribute to the partial metabolism and production of more immunogenic peptides that can better cross the epithelial barrier. Once crossed, the peptides undergo further processing, particularly demadidation, which confers high binding afinity to HLA-DQ2/8.
Yes! There are certain gut microbes with gluten-degrading and -modifying properties, which we believe could play an important role in the context of celiac disease, influencing both its pathogenesis and potential mitigation
December 11, 2024 at 2:36 PM
Yes! There are certain gut microbes with gluten-degrading and -modifying properties, which we believe could play an important role in the context of celiac disease, influencing both its pathogenesis and potential mitigation