Hallez Lab
@hallezlab.bsky.social
@frsFNRS Senior Research Associate @UNamur interested in Bacterial Cell cycle #caulobacter and Stress Response #StringentResponse #alarmone #ppGpp
Reposted by Hallez Lab
The wonderful dynamics of (p)ppGpp, big thank you to everyone involved with this story
www.nature.com/articles/s41...
www.nature.com/articles/s41...
(p)ppGpp imposes graded transcriptional changes to impair motility and promote antibiotic tolerance in biofilms - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - (p)ppGpp imposes graded transcriptional changes to impair motility and promote antibiotic tolerance in biofilms
www.nature.com
August 1, 2025 at 7:15 PM
The wonderful dynamics of (p)ppGpp, big thank you to everyone involved with this story
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Hallez Lab
Happy to share our lastest story about the Stringent Response ! We show how host-relevant stress disrupts Fe-S cluster stability, tuning (p)ppGpp levels to control bacterial adaptation and trigger virulence.
Read more here 👉 www.biorxiv.org/content/10.1...
Read more here 👉 www.biorxiv.org/content/10.1...
Stress-Induced Iron-Sulfur Cluster Damage as a Conserved Trigger of the Stringent Response
Pathogenic bacteria rely on the stringent response to adapt to the complex and fluctuating conditions encountered within the host. However, the mechanisms by which the stringent response senses host-i...
www.biorxiv.org
July 30, 2025 at 10:53 AM
Happy to share our lastest story about the Stringent Response ! We show how host-relevant stress disrupts Fe-S cluster stability, tuning (p)ppGpp levels to control bacterial adaptation and trigger virulence.
Read more here 👉 www.biorxiv.org/content/10.1...
Read more here 👉 www.biorxiv.org/content/10.1...