Humanytip
guidedfocus.bsky.social
Humanytip
@guidedfocus.bsky.social
“What we observe is not nature itself, but nature exposed to our method of questioning.”
~ Werner Heisenberg
A large protective factor is the level of mindfulness (which can be cultivated). Studies consistently indicate that trait mindfulness is associated with less amyloid, tau, and cognitive decline – for example see: pubmed.ncbi.nlm.nih.gov/36712573/
Trait Mindfulness Is Associated With Less Amyloid, Tau, and Cognitive Decline in Individuals at Risk for Alzheimer's Disease - PubMed
Trait mindfulness was associated with less cognitive decline and less Aβ and tau in the brain in older adults at risk for AD dementia. Longitudinal studies examining the temporal relationship between ...
pubmed.ncbi.nlm.nih.gov
August 7, 2025 at 10:45 PM
In the summary (of the book) she has provided, the word 'psychosocial' does not exist!
July 29, 2025 at 2:16 PM
Do you think the book ignores psychosocial factors, which are the most influential factors for mental ill-health?
July 28, 2025 at 5:44 PM
The following sentence in the article needs a reference source, because it is not supported by science: “..the risks of untreated mental illness, especially during pregnancy, tend to outweigh the small and uncertain risk of antidepressants harming unborn babies..”
July 26, 2025 at 2:15 AM
There are psychological therapies that can treat depression very effectively, without the use of medications (that may have the potential for dangerous side-effects). See for example: pubmed.ncbi.nlm.nih.gov/38360361/
Effects of mindfulness-based interventions (MBIs) on depression in pregnant women: A systematic review and meta-analysis - PubMed
Mindfulness-based interventions significantly improved depression among pregnant women, especially mindfulness-based cognitive therapy (MBCT). Clinicians and health providers should consider using MBI...
pubmed.ncbi.nlm.nih.gov
July 26, 2025 at 2:14 AM
Reposted by Humanytip
Those who choose to live near a golf course can be older or individuals who prefer golf due to chronic conditions that prevent them from participating in more challenging sports. So, these individuals would be more prone to Parkinson’s anyway..
May 14, 2025 at 5:14 PM
4/4. Considering all this, I think you could update your paper and publish again (perhaps in a different journal), because this is an important aspect of mindfulness that needs to be understood.
July 26, 2025 at 2:02 AM
3/4. Regarding the first point, mindfulness-related changes also can have a ceiling effect. In Kral (2022) paper (cited in your paper, which accounts for a high number of participants, without brain changes) had unusually healthy people with very low negative affect (they state this).
July 26, 2025 at 2:01 AM
2/4. This is similar to how only unfit people would develop changes in muscle mass following exercise. In fit people, changes in muscle-mass (following exercise) would not be seen due to a ceiling effect.
July 26, 2025 at 2:01 AM
1/4. Hi Junhong: I think for structural changes in the brain to happen (following mindfulness), one has to be experiencing negative affect – i.e., when someone’s stress, anxiety, etc., are reduced (via mindfulness training), then brain changes can be observed.
July 26, 2025 at 2:00 AM
There are psychological therapies that can treat depression very effectively, without the use of pills (that are mostly guess work). See for example: pubmed.ncbi.nlm.nih.gov/36186359/
Effect of mindfulness meditation on depression during pregnancy: A meta-analysis - PubMed
Mindfulness meditation can improve the prevention, remission, and reduction of depression during pregnancy and can be used as an auxiliary measure for the clinical treatment of pregnancy depression.
pubmed.ncbi.nlm.nih.gov
July 25, 2025 at 11:05 PM
The sentence “..the risks of untreated mental illness, especially during pregnancy, tend to outweigh the small and uncertain risk of antidepressants harming unborn babies..” – This is an opinion that is not supported by science. Please cite a reference for this sentence.
July 25, 2025 at 10:58 PM
Brain changes happen as a result of rumination following psychological stress, and interventions addressing rumination (e.g. mindfulness interventions) can reverse such changes (see below article). This study that focus only on brain changes is misleading. pmc.ncbi.nlm.nih.gov/articles/PMC...
Neurobiological Changes Induced by Mindfulness and Meditation: A Systematic Review
Background and Objectives: Meditation and mindfulness, rooted in ancient traditions, enhance mental well-being by cultivating awareness and emotional control. It has been shown to induce neuroplastici...
pmc.ncbi.nlm.nih.gov
July 5, 2025 at 10:07 PM
Psychological stress followed by rumination lead to many brain changes (see the article below), and interventions addressing stress (e.g. mindfulness interventions) can *reverse* such changes. Studies that focus only on brain changes can be misleading. www.sciencedirect.com/science/arti...
Rumination and the default mode network: Meta-analysis of brain imaging studies and implications for depression
Rumination is strongly and consistently correlated with depression. Although multiple studies have explored the neural correlates of rumination, findi…
www.sciencedirect.com
July 5, 2025 at 10:00 PM
Profit-driven drugs are not the solution to all problems though. We need to get over the a ‘drug for everything’ mentality, which can lead to many problems including a reduced quality of life for people.
June 7, 2025 at 1:13 AM
Profit-driven drugs are not the solution to all problems though. We need to get over the a ‘drug for everything’ mentality, which can lead to many problems including a reduced quality of life for people.
June 7, 2025 at 1:12 AM
Any distress in meditation happens due to not understanding what exactly one is doing during meditation. Meditation is about letting go, & focusing on the present moment – it is not about holding on to any stress/discomfort even if they arise from the meditation itself.
June 3, 2025 at 10:04 PM
This makes a lot of sense, especially in light of the numerous challenges currently confronting conventional psychiatric treatments. A key factor in the resistance to change may lie in the profit motives associated with pharmaceutical interventions.
May 20, 2025 at 10:39 PM
But no one has found genes for 'mental disorders,' and psychosocial factors play a significant role in their development. Also, people are able to better deal with so called ‘mental disorders’ through mental-training such as mindfulness practices. See for example: pubmed.ncbi.nlm.nih.gov/36979294/
Effects of Mindfulness-Based Interventions (MBIs) in Patients with Early-Stage Alzheimer's Disease: A Pilot Study - PubMed
Bachground In this study, we hypothesize that mindfulness-based interventions (MBIs) may improve well-being and the related outcomes in Alzheimer's dementia patients (AD-P) at an early stage. MBIs con...
pubmed.ncbi.nlm.nih.gov
May 17, 2025 at 10:50 PM
Those who choose to live near a golf course can be older or individuals who prefer golf due to chronic conditions that prevent them from participating in more challenging sports. So, these individuals would be more prone to Parkinson’s anyway :)
May 14, 2025 at 5:17 PM