Aleksandra Gruevska
@gruevska.bsky.social
Research Associate, Imperial College London @imperialmdr.bsky.social
Lipid metabolism in chronic liver disease and HCC. Mass spec imaging.
#Liversky #MassSpec #spatial #metabolomics
https://profiles.imperial.ac.uk/a.gruevska
Lipid metabolism in chronic liver disease and HCC. Mass spec imaging.
#Liversky #MassSpec #spatial #metabolomics
https://profiles.imperial.ac.uk/a.gruevska
Using #massspecimaging we show #lipid #metabolism is dysregulated spatially in #liverfibrosis. By integrating MSI and IMC, we linked #sphingolipids with non-parenchymal cells. Targeting sphingolipid metabolic pathway in HSCs and hPCLSs showed anti-fibrotic effect.
April 23, 2025 at 2:58 PM
Using #massspecimaging we show #lipid #metabolism is dysregulated spatially in #liverfibrosis. By integrating MSI and IMC, we linked #sphingolipids with non-parenchymal cells. Targeting sphingolipid metabolic pathway in HSCs and hPCLSs showed anti-fibrotic effect.