www.youtube.com/shorts/T71nF...

Hi Scott,

Waiting for the madness to calm down, and seeing what the destruction of our NIH, FDA, and Medicaid will yield as many of my stocks, BNGO included, have a dependency on these.

In times of madness, posting about stocks is futile, but still watching, daily, and day trading. We'll see.

Yes, that's correct.

A combination of the SP at the time, Q4 2023 sales which they will know about, and reimbursement which will kick in soon, will go into the decision as to which ratio they choose.

Too high a ratio and it will simply plummet - 25/1 is my guess if things are looking up.

Cathie Wood has undeniably had an atrocious 2024 in terms of her high profile investments !

PacBio is an interesting one : their Revio is quite simply overpriced, and that's before next year's tariffs and inflation, so the outlook is poor + cheaper Oxford Nanopore is making serious waves ...

The 5 Belgium universities/hospitals were :
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Ghent University Hospital, Ghent
Ghent University
University Hospital Leuven, Leuven
Antwerp University Hospital, Antwerp
University of Antwerp

www.nature.com/artic...
5/5

conditions.

Conclusion : both LRS and OGM need each other and when combined they provide a full and precise diagnosis not available through SOC molecular techniques.
4/5

The clinical scientists used Oxford Nanopore Long-Read sequencing and Optical Genome Mapping (OGM) and found that the combination of both these techniques provided a most powerful molecular diagnosis method which finally enabled them to fully characterize the SVs involved in these patients'
3/5

The paper details a study of 6 patients with Structural Variants unresolved through Standard of Care techniques (routine molecular techniques - Karyotyping, FISH, Short-Read Sequencing).
2/5

www.politico.com/news/magazin...

approach is desirable to overcome the limitations of the current Standard of Care.

onlinelibrary.wiley....
8/8

So much so that in their conclusion the scientists stated :

"It is possible that technology such as OGM will identify similar events in other cases, and possibly help uncover previously unknown mechanisms of human disease."

The scientists conclude that in genetic diseases a multi-omics
7/8

material from chromosome 17 undetected by Karyotyping or rGS. These novel mechanisms revealed by OGM were critical to the eventual diagnosis of the patient.
6/8

OGM not only confirmed the clinicians' suspicions but, additionally, contrary to the SVs suggested by Karyotyping and rGS (rapid Genome Sequencing) demonstrated the presence of an unbalanced translocation involving chromosomes 22 and 17, with loss of material from chromosome 22, and a gain of
5/8

At this point they turned to OGM for a more precise molecular diagnosis.
4/8

In this particular case, a patient's observable signs were so severe that, when taking into account that they had already discovered a previously unknown translocation, the clinicians suspected there might be additional breakpoints and/or translocations involved.
3/8

is a genetic disorder which can cause a wide range of symptoms varying in severity. These symptoms could include global developmental delay/intellectual disability, motor skills deficits, delayed or absent speech, autism spectrum disorder, and minor dysmorphic features.
2/8

IGNORE - 20 minutes later all good throughout.

Not sure what happened, but all good !

Thank You !