Victor Tatarskiy
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greenrat.bsky.social
Victor Tatarskiy
@greenrat.bsky.social
1.9K followers 3.3K following 3.8K posts
Cell biologist and a cat person. I mainly study CDK8/19, cell cycle regulation, and new anti-cancer drug candidates.
https://orcid.org/0000-0002-9080-5683
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greenrat.bsky.social
regarding autism rates - recent article by Dr Richard Grinker www.nytimes.com/2025/09/24/o... (and in more detail in podcast why-is-this-happening-with-chris-hayes.simplecast.com/episodes/how...) gave a fascinating fact - the enrollment for special education does not change much, just the labels:
The proportion of children receiving special education services in the United States has had only a small increase over the past couple of decades, but the labels have changed. Many children who once might have been classified as having an intellectual disability, emotional disturbance or specific learning disability are now classified as having autism. Indeed, one study of special education enrollment data on 6.2 million schoolchildren between 2000 and 2010 found that the reduction of intellectual disability classifications alone accounted for 64 percent of the rise in autism classifications during that decade. Such reclassification helps explain how what may seem like an epidemic may actually be the result of greater awareness and changing definitions.
December 1, 2025 at 12:51 PM
greenrat.bsky.social
regarding autism rates - recent article by Dr Richard Grinker www.nytimes.com/2025/09/24/o... (and in more detail in podcast why-is-this-happening-with-chris-hayes.simplecast.com/episodes/how...) gave a fascinating fact - the enrollment for special education does not change much, just the labels:
from NYT https://www.nytimes.com/2025/09/24/opinion/autism-rates-science-diagnosis-parent.html By Roy Richard Grinker Dr. Grinker is a cultural anthropologist and the author of “Unstrange Minds: Remapping the World of Autism.” The proportion of children receiving special education services in the United States has had only a small increase over the past couple of decades, but the labels have changed. Many children who once might have been classified as having an intellectual disability, emotional disturbance or specific learning disability are now classified as having autism. Indeed, one study of special education enrollment data on 6.2 million schoolchildren between 2000 and 2010 found that the reduction of intellectual disability classifications alone accounted for 64 percent of the rise in autism classifications during that decade. Such reclassification helps explain how what may seem like an epidemic may actually be the result of greater awareness and changing definitions.
December 1, 2025 at 12:48 PM
greenrat.bsky.social
Celebrating my grandmothers 88. Less and less friends are alive, and can come, but I always loved their parties and stories.
My grandmother Irina is 88 today. Celebration of my grandmothers 88
November 30, 2025 at 4:34 PM
greenrat.bsky.social
I'm not an expert on this pathway - at a glance:
things wrong with the picture, IMO
November 21, 2025 at 1:52 PM
greenrat.bsky.social
also :))
Martin, looking great in a hat :))
November 13, 2025 at 8:42 AM
greenrat.bsky.social
Neat trick if you polycolonal ab's suck. Incubate them with fixed cells with a KO of your protein of interest, then spin. Protocol here: www.med.upenn.edu/markslab/ass...
I was amazed how well it worked on first try (I'm sure that I can completely eliminate unspecific bands)
#WesternBlot #cellsky
On the left - western blot of B16F10 cells wt and KO for CDK8. Our in house produced antibodies give a lot of unspecific bands. On the right same probes with antibodies preincubated with fixed CDK8 KO cells - there is a specific band and faint unspecific bands, which can be probably eliminated with increase of amount of KO cells.
October 2, 2025 at 5:11 PM
greenrat.bsky.social
Tired of illustrating survivorship bias with the Wald's chart of a WW2 bomber? Use Marshall Oudinot instead! :))
A white silhouette of Marshal Oudinot with red dots indicating his wounds Marshal Nicolas Oudinot died in Paris at the ripe old age of 80, while serving as Governor of Les Invalides. Oudinot was famous for his bravery in battle, and for receiving more wounds - 34 - than any other of Napoleon’s Marshals. Years after the Napoleonic Wars, Oudinot was taking the waters at a spa with a fellow officer, Canrobert, who saw his scarred body and observed that Oudinot was ‘nothing more than a colander.’ Illustration of hypothetical damage pattern on a WW2 bomber. Loosely based on data from an unillustrated report by Abraham Wald (1943), showing that a similar plane survived a single hit to the engine 60% of the time, but a hit to the fuselage or fuel system closer to 95% of the time. Picture is based on US Air Force "hit plots", such as this F-4 hit plot published in 1991. New version by McGeddon based on a Lockheed PV-1 Ventura drawing (2016), vector file by Martin Grandjean (2021).
September 17, 2025 at 1:01 PM
greenrat.bsky.social
Same energy
Squirrel form the Ice Age in mid-jump
September 1, 2025 at 2:11 PM
greenrat.bsky.social
O, wow, how cool I am. Single-handedly did the Peace of Westphalia, apparently!
An email from Goodreads - "You've just finished The Thirty Years War. What's next?"
August 27, 2025 at 1:09 PM
greenrat.bsky.social
No new pictures, where you at mentally?
A picture of a redhead girl with a giant black goat behind her with his heaf kn her shoulder
August 25, 2025 at 5:04 PM
greenrat.bsky.social
An academic editor posted this pic. Yikes.

Done with two reviews this week, accepted three more, doing my part :-\
An editor's dashboard with 2 accepted reviewer invitations and 51 declined
August 7, 2025 at 9:48 AM
greenrat.bsky.social
BRB
Painting of Elizabeth I of England, also known as the Ermine Portrait. Elizabeth is wearing a richly decorated black dress and The Three Brothers jewel.
August 5, 2025 at 9:48 AM
greenrat.bsky.social
Oh, it's me again with our favorite rubric - "they already did that in the worst times of Soviet Union". This time Stalin's repression of statisticians and falsification of census data

dmo.econ.msu.ru/demografia/R...
(nowadays they just stop publishing "bad" data)
During the Great Terror of 1937-1939, statistical personnel, including organizers of the disavowed 1937 census, paid with their lives for their attempt to adhere to professional standards – during these years, three successive heads of the Central Statistical Administration were executed, and many others statisticians were arrested (see, e.g.: Volkov, 1990). The total number of those who perished in the Great Terror is believed to have reached two million (Andreev and Kharkova, 2001; for alternative lower recent estimates, e.g., see: Getty and Naumov, 1999, Appendix 1).4
August 4, 2025 at 2:07 PM
greenrat.bsky.social
*was wrong - lions and unicorns on stuff. The most unique example comes from the Moscow Printing Yard building, which had a lion and unicorn on its gates. Later was rebuilt with the same duo, there to this day (although now with the USSR crest, not the Eagle)
Old (second) Moscow Printing Yard, built during Michael's I reign after the fire destroyed the first one. It has a Unicorn and a Lion on it's gates, under the double headed Eagle The new building, now the Russian Humanitarian University, built in the 19 century. The Unicorn and the Lion are still there, but above them is the Soviet coat of arms replacing the double headed Eagle after the revolution. The oldest printing yard buildings from the 16-17 century are inside the complex
August 3, 2025 at 8:15 AM
greenrat.bsky.social
I googled, and wiki said that there are two interpretations :))
List of humorous units of measurement Wikipedia https://en.wikipedia.org › wiki › List_of_humorous_uni... One furlong per fortnight is very nearly 1 centimetre per minute (to within ... Scaramucci. A Scaramucci (or Mooch) is 11 (sometimes 10) days and is ...
July 30, 2025 at 8:59 PM
greenrat.bsky.social
The little book
A huge 3000 page book with red bunder
July 28, 2025 at 6:30 PM
greenrat.bsky.social
No cheating, post your lock screen!

I have 7 changing ones
A plan of a star fortress A full closed 15 century helmet A painting of a spanish princess (?) An astrolaby with a dragon head
July 27, 2025 at 3:17 PM
greenrat.bsky.social
I knew that Western blots were sacrifices to the gods.
A page from The Long Millennium Affluence, Architecture and Its Dark Matter Economy about Vikings sacrificing stuff into rivers and bogs, with the sacrifices being called blots
July 27, 2025 at 11:31 AM
greenrat.bsky.social
Collected my tribute
Green and red gooseberries
July 26, 2025 at 10:51 AM
greenrat.bsky.social
Anything becomes French if you put a La before it (and yes this whole overview is wrong on so many levels)
Google AI overview about the phrase "The quick brown fox jumps over the lazy dog" correctly stating that the sentence has all the letters of English language, then translating it to Spanish (where the rule does not stand), and then to "French" which is actually Ukranian, just starting with "La" for some reason.
July 25, 2025 at 9:15 PM
greenrat.bsky.social
A six-panel comic shows two cartoon characters: one blue with a Democratic Party "D" symbol and one green wearing a red "Make America Great Again" hat. In the first panel, the green character tells the blue one that pressing a red button will send Donald Trump to prison for life. In the second panel, the green character adds that Bill Clinton will also get the same punishment, trying to dissuade the blue character. Despite this, the blue character presses the button in the next panel. The fourth panel shows the green character nervously watching as the blue character continues to press the button repeatedly. In the fifth panel, the button makes loud "BIP!" sounds while the blue character keeps pressing. In the final panel, the green character tries to stop the blue character, saying "no wait," as the button continues to beep rapidly.
July 25, 2025 at 12:05 AM
greenrat.bsky.social
The monument of me battling my ADHD - my day by day list of tasks (currently unique tasks 392 recorded this year, but I was slacking for a few month). Doing this for two years now (and finally maintaining a calendar consistently)

#ADHD
my tasks list - name of tasks, priority, time spent on each, notes, graphs etc
July 23, 2025 at 10:41 PM
greenrat.bsky.social
made a modified @xkcd.com meme to cheer me up
the xkcd meme with the researcher killing cancer cells in a dish with a gun, with the gun replaced by a small tank
July 23, 2025 at 1:07 AM
greenrat.bsky.social
"Why is when something happens it is always you three"
DCI Carl Morck (Matthem Goode), DC Rose Dickson (Leah Byrne), and Akram Salim (Alexey Manjelov) being called by very displeased Moira Jacobson (Kate Dickie). From Dept Q (Netflix)
July 20, 2025 at 8:30 PM
greenrat.bsky.social
WaPo sent me this (see picture) Wondering what are the others (my version)
1) Not checking sequences of expression vectors
2) Forgetting about post-translational modifications
3) Using non-validated antibodies
4) Using the wrong expression system
5) Not adding protease inhibitors
A letter from WaPo - You might be fooling yourself about peanut butter, plus 5 other protein mistakes
July 18, 2025 at 5:49 PM