Green Ahn
@greenahn.bsky.social
JCC HHMI Postdoctoral fellow in David Baker lab at IPD. PhD in Chemistry from Bertozzi lab at Stanford.
and (ii) engineer buried charged networks inside the binder to destabilize the binder while preserving the interface residues.
October 1, 2025 at 4:22 PM
and (ii) engineer buried charged networks inside the binder to destabilize the binder while preserving the interface residues.
We combined Rosetta and deep-learning based methods to (i) weaken the binder-target interface by inducing electrostatic repulsion upon histidine protonation
October 1, 2025 at 4:22 PM
We combined Rosetta and deep-learning based methods to (i) weaken the binder-target interface by inducing electrostatic repulsion upon histidine protonation