Grant Nickles
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grantnickles.bsky.social
Grant Nickles
@grantnickles.bsky.social
Cyclist, mycologist, music, and hockey 🏳️‍🌈

https://gnick18.github.io/

@NSF GRFP fellow studying fungal evolution and natural products in the Keller Lab
Thanks Rauf!
May 30, 2025 at 4:08 AM
Thanks Mark! Happy I get to stay with my Madison colleagues
May 30, 2025 at 4:08 AM
(6/x) And that this fall I will be starting my own interdisciplinary postdoctoral research program at UW-Madison that will be at the intersection of proteomics, genomics, and natural products (managing my own budget and everything 🥹).
May 29, 2025 at 10:44 PM
(5/x) All of that to say, I’m happy to announce that I am now Dr. Nickles (PhD).
May 29, 2025 at 10:44 PM
(4/x) Weeks prior I was questioning if I was going to have to quit science altogether. Am just overwhelmed and beyond grateful for this opportunity. I can’t thank Dr. Nancy Keller and Dr. Milton Drott enough for their mentorship.
May 29, 2025 at 10:44 PM
(3/x) The day of my defense, 55 min before it was to start, I got an email from UW-Madison notifying me that the school is giving me 250k to start my own research program under the mentorship of two amazing professors. All on a proposal I CAME UP WITH AND WROTE on antimicrobial drug discovery.
May 29, 2025 at 10:44 PM
(2/x) I had been trying to obtain a postdoc or industry science position for the last 8 months. Several opportunities had been taken away from me from federal cuts to science. Nearly 100 applications later I went into my PhD defense bittersweet that I was graduating but into nothing.
May 29, 2025 at 10:44 PM
Thanks Dan !!
May 14, 2025 at 5:09 PM
Nice catch at thanks for clarifying. I do mean CDT!
May 12, 2025 at 11:58 PM
3. The invasion of Amanita muscaria 🍄 into South Africa, viewed through a natural product lens! I'll discuss its geographic origins & the role its specialized metabolites may have played in its global success as an invader. (in revision)
May 12, 2025 at 11:15 PM
2. The stepwise evolution of a highly unusual ICS-NRPS-like hybrid megasynthase! This fun story started with a targeted search into lichen BGC biodiversity, leading us to uncover the evolutionary origins of this 'one-enzyme' metabolic pathway now found in ~30% of Ascomycetes. (in preparation)
May 12, 2025 at 11:15 PM
1. The evolution and diversity of a new class of fungal natural products that I characterized in 2023 (isocyanide synthase BGCs), where I showed they're the 5th most common BGC class in fungi! academic.oup.com/nar/article-...
May 12, 2025 at 11:15 PM
April 2, 2025 at 2:41 AM
OH HELL YA NOT ANYMORE YIPPIIIIEEEEEEE
April 2, 2025 at 1:58 AM