Gordian Biotechnology
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gordianbio.bsky.social
Gordian Biotechnology
@gordianbio.bsky.social
Our mission is to cure age-related disease by moving successful therapeutics toward clinical trials within months, not years. #CreatingTime
Check out chief science officer @martinbjensen.bsky.social’s post tackling misconceptions about AAV gene therapy only being best suited for rare diseases, and how factors like cost would be very different for common diseases like Parkinson’s, heart failure, and arthritis.
March 25, 2025 at 1:51 PM
Check out vector engineering research associate Chase Bowman performing ultracentrifugation density gradient separation. Not familiar with the process?
March 20, 2025 at 3:00 PM
We used the time to celebrate everything we’ve accomplished over the past year and map out ambitious plans for clinical development of our lead therapies!

#Biotech
#TeamBonding
#InVivoResearch
March 13, 2025 at 3:05 PM
Last month, we traded the lab for the mountains, heading to Tahoe for a well-earned winter retreat. 🏔️⛷️

As evidenced in the photos, the weather cooperated, and we all were rejuvenated by the gorgeous scenery, time outdoors, and team bonding.
March 13, 2025 at 3:05 PM
Big (belated) congrats to Alex Araki! 🎉 Formerly a research associate on our in vivo team, Alex defended his thesis & earned a well-deserved promotion to scientist! We’re so proud of him and excited to see all the amazing work he’ll do in this next chapter!
March 6, 2025 at 3:53 PM
ICYMI, co-founders Francisco LePort and @martinbjensen.bsky.social were guests of Dr. Moira Gunn on the BioTech Nation podcast.

It ran on our hometown NPR station KQED and about 200 other @npr.org affiliates.
February 3, 2025 at 3:55 PM
If you don’t already subscribe to the BioTech Nation podcast with Dr. Moira Gunn, you will now!
January 30, 2025 at 5:41 PM
Gordian has redesigned the preclinical process from the ground up. All drug developers must validate in animals. Gordian trains for discovery in animals from step one. Our preclinical discovery process takes place entirely in vivo. (🧵6/9)
November 20, 2024 at 2:32 PM
A tell-tale sign that we haven’t taken full advantage of new tools and AI is that souped up preclinical processes look essentially the same, just with AI and robotics added. Here is Recursion’s 17 step preclinical process: bit.ly/4fwB2TF. In vivo validation doesn’t come until step 17. (🧵4/9)
November 20, 2024 at 2:32 PM
AI, robotics, and new -omics have made this process much more efficient, but it is still the same fundamental discovery process. This image pulled from a quick Google search summarizes the process in 12 (not so) easy steps. In vivo validation comes in at step 12. (🧵3/9)
November 20, 2024 at 2:32 PM
The success of AI applied to drug discovery is being decided by a number of clinical trials. So far, the results are lackluster. Why? For AI to have a transformational effect in drug discovery, training data must come from living mammals. (🧵1/9)
November 20, 2024 at 2:32 PM