JX Chen
@gobiologycn.com
Phylogenomics | Systematics | Natural History | Biodiversity
http://www.gobiologycn.com/ABOUT_ME/aboutme.html
http://www.gobiologycn.com/ABOUT_ME/aboutme.html
Reposted by JX Chen
Quest for Orthologs 8 meeting report/review: where AI, protein structure, isoforms & domains meet orthology. We review recent developments in the field, with applications from environmental genomics to agriculture. Many authors, led by @irenejulca.bsky.social. Open access: doi.org/10.1007/s002...
Quest for Orthologs in the era of Data Deluge and AI: Challenges and Innovations in Orthology Prediction and Data Integration - Journal of Molecular Evolution
The rapid advancement of DNA sequencing technologies and computational algorithms has led to an unprecedented surge in genomic data, driven by several large-scale sequencing projects worldwide. Orthol...
doi.org
October 23, 2025 at 6:22 AM
Quest for Orthologs 8 meeting report/review: where AI, protein structure, isoforms & domains meet orthology. We review recent developments in the field, with applications from environmental genomics to agriculture. Many authors, led by @irenejulca.bsky.social. Open access: doi.org/10.1007/s002...
Reposted by JX Chen
Gene annotations matter for downstream analyses: different structural gene-annotation pipelines yield markedly different orthology calls. We compare four strategies across species and argue for standards & QC before inference. Work led by @silviaprietob.bsky.social. Paper: doi.org/10.1093/bioi...
October 23, 2025 at 6:20 AM
Gene annotations matter for downstream analyses: different structural gene-annotation pipelines yield markedly different orthology calls. We compare four strategies across species and argue for standards & QC before inference. Work led by @silviaprietob.bsky.social. Paper: doi.org/10.1093/bioi...
Reposted by JX Chen
Even more exciting is we find evidence for functional convergence over a macroevolutionary scale spanning 50 million years!! In mini species, growth inhibitor genes (ING2 and CDKN1B) are expressed at higher levels, while in large-bodied species the growth-factor gene TGFB3 is expressed more.
October 22, 2025 at 9:39 PM
Even more exciting is we find evidence for functional convergence over a macroevolutionary scale spanning 50 million years!! In mini species, growth inhibitor genes (ING2 and CDKN1B) are expressed at higher levels, while in large-bodied species the growth-factor gene TGFB3 is expressed more.