Samantha Sanford
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glowingtelomeres.bsky.social
Samantha Sanford
@glowingtelomeres.bsky.social
Postdoc studying telomeres and telomerase at the University of Pittsburgh in the @opreskolab.bsky.social 👩‍🔬🧬☢️
Reposted by Samantha Sanford
I am excited to share that our study has just been published in Nature Communications! www.nature.com/articles/s41...
We uncovered a “dark side” of base excision repair of oxidative guanine damage at telomeres.
🧵⬇️
OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced senescence in human fibroblasts - Nature Communications
Telomeres are prone to oxidative damage, particularly the formation of the common lesion 8-oxoguanine. This study shows that the processing of 8-oxoguanine at telomeres by the DNA repair enzymes OGG1 ...
www.nature.com
January 27, 2025 at 2:16 PM
Reposted by Samantha Sanford
It's coffee break time, but our lab elf might have a better idea with a mug of hot cocoa and a cozy blanket!
@opreskolab.bsky.social @glowingtelomeres.bsky.social @meryderosa.bsky.social
December 13, 2024 at 8:21 PM
A few of my favorite sunset photos taken last month in Greece during the EMBO DNA damage meeting
November 21, 2024 at 6:12 PM