glicholai.bsky.social
@glicholai.bsky.social
Wake up after midnight? Don’t worry—you’re in good company. From Odysseus to 14th-century monks, people once embraced a quiet or even productive interlude before returning to their ‘second sleep.’ So enjoy the pause and maybe even dream of Penelope!

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Second Sleep: The Medieval Intermission Your Body Still Remembers | Greg Licholai
Wake up after midnight? Don’t worry—you’re in good company. From Odysseus to 14th-century monks, people once embraced a quiet or even productive interlude before returning to their ‘second sleep.’ So ...
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November 11, 2025 at 4:35 PM
From citrus tests aboard 18th-century ships to today’s randomized controlled trials, the RCT transformed healing from ritual into science—revealing that even “nothing” could be powerful when measured with rigor. www.linkedin.com/pulse/rise-r...?
🧪The Rise of the Randomized Controlled Trial (RCT): The Power of Nothing
Long before “evidence-based medicine” became dogma, doctors practiced its opposite—with confidence. In the 18th and 19th centuries, the most potent drugs often did little, and the least potent sometim...
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November 4, 2025 at 8:44 PM
Digital twins are now being explored as tools to improve surgical planning, reduce errors, and even assist robotic procedures in real time. These virtual replicas of physical systems that learn, simulate, and predict performance.
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Innovative Healthcare Leadership | Dr. Greg Licholai
Dr. Greg Licholai combines medicine, business, and policy expertise to drive innovation in healthcare and biotechnology, shaping the future of drug development.
licholai.com
October 31, 2025 at 1:51 PM
The U.S. once set the global pace in drug discovery. Now, as China accelerates and our own innovation engine slows under regulation, the question isn’t can we lead again—it’s whether we’ll have the courage to reinvent how we govern science itself.
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💊 America’s Medicine Future: Can We Still Lead the World in Drug Discovery?
For most of the past century, the United States has been the superpower of medical innovation. Our universities, entrepreneurs, and regulators built the modern pharmaceutical industry—and gave the wor...
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October 28, 2025 at 5:51 PM
New blood test capable of detecting more than 50 types of cancer has delivered highly promising results in one of the largest interventional screening trials to date
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Blood Test Detects Dozens Of Cancers Early
Blood Test Breakthrough Detects Dozens of Cancers Early With Unprecedented Accuracy
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October 19, 2025 at 1:13 PM
Pfizer plants a big flag in the obesity market and makes huge bet on Metsera
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Pfizer Bets Big On Obesity Market
Pfizer $4.9 billion cash acquisition of Metsera, a clinical-stage biotech focused on next-generation obesity drugs
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October 3, 2025 at 6:36 PM
For the first time researchers have used generative AI to predict individual health risks. This is a scientific milestone for the future of medicine, prevention, and policy.
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Predicting Human Disease With Generative Models
Researchers use generative AI to predict individual health risks
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October 1, 2025 at 4:58 PM
American leadership in developing innovative medicines is getting bogged down but REGULATORY PRAGMATISM can have quick impact.

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Reclaiming America’s Drug Innovation Edge
Decline of American leadership in drug innovation
www.forbes.com
September 26, 2025 at 10:02 PM