Gita Abhiraman
@gitaabhiraman.bsky.social
MD/PhD Student at Stanford interested in immune signaling, protein engineering, autoimmunity and cancer. PhD with Chris Garcia on a Hertz fellowship.
Conversely, we show that cytokine adaptors can convert inflammatory cytokines into immunosuppressive signals. We show conversion of IL-23 or IL-17 into immunosuppressive IL-10 receptor agonists, with potential applications in autoimmune disease.
March 12, 2025 at 1:35 AM
Conversely, we show that cytokine adaptors can convert inflammatory cytokines into immunosuppressive signals. We show conversion of IL-23 or IL-17 into immunosuppressive IL-10 receptor agonists, with potential applications in autoimmune disease.
As proof of concept, we design cytokine adaptors that convert TGF-b or IL-10 into IL-2 receptor agonists to reverse T cell suppression, with potential applications in cancer therapy.
March 12, 2025 at 1:35 AM
As proof of concept, we design cytokine adaptors that convert TGF-b or IL-10 into IL-2 receptor agonists to reverse T cell suppression, with potential applications in cancer therapy.
Conversely, we show that cytokine adaptors can convert inflammatory cytokines into immunosuppressive signals. We show conversion of IL-23 or IL-17 into immunosuppressive IL-10 receptor agonists, with potential applications in autoimmune disease.
March 12, 2025 at 1:33 AM
Conversely, we show that cytokine adaptors can convert inflammatory cytokines into immunosuppressive signals. We show conversion of IL-23 or IL-17 into immunosuppressive IL-10 receptor agonists, with potential applications in autoimmune disease.
As proof of concept, we design cytokine adaptors that convert TGF-b or IL-10 into IL-2 receptor agonists to reverse T cell suppression, with potential applications in cancer therapy.
March 12, 2025 at 1:33 AM
As proof of concept, we design cytokine adaptors that convert TGF-b or IL-10 into IL-2 receptor agonists to reverse T cell suppression, with potential applications in cancer therapy.
Applications are open for Gates Grand Challenges - funding for projects spanning antibiotic discovery, menstrual bleeding, HIV/TB diagnosis, women’s health, and preeclampsia. Feel free to share. DM me for the email/links.
February 25, 2025 at 1:00 AM
Applications are open for Gates Grand Challenges - funding for projects spanning antibiotic discovery, menstrual bleeding, HIV/TB diagnosis, women’s health, and preeclampsia. Feel free to share. DM me for the email/links.