gi-baumgartner.bsky.social
@gi-baumgartner.bsky.social
Physician scientist interested in host microbiome interactions, Postdoc Campbell lab CeMM Vienna
doi.org/10.1111/nmo....
We show lower transit time alone decreases microbiome diversity + BA metabolism and increases fecal BA. Many 'omics studies and breath testing (SIBO) don't take this into account, hindering true progress on IBS/IBD pathomechanism.
#gastrosky #MedSky
Changing Gastrointestinal Transit Time Alters Microbiome Composition and Bile Acid Metabolism: A Cross‐Over Study in Healthy Volunteers
Alterations in whole gut transit time (WGTT) significantly impact microbiome composition and bile acid metabolism. Using senna and loperamide, we show that WGTT changes influence bacterial diversity,....
doi.org
May 25, 2025 at 11:39 AM
Looking forward to present my talk about "Epimerization of Host-Derived Bile Acids By Ruminococcus gnavus
as a Hallmark of Microbiota Dysbiosis" at #KSHumanMicro25 #KSHostMicrobe25

Connecting bacteria to specific metabolites, will enhance out mechanistic understanding of IBD.
#gastrosky #MedSky
February 16, 2025 at 6:51 PM
BS and UC have endoscopically visible mucosal biofilms that represent a disrupted microbiome and Bile acid malabsorption as possible mechanism of diarrhea.

www.gastrojournal.org/article/S001...

#gastrosky #MedSky
@gastroenterology.bsky.social
February 16, 2025 at 6:41 PM