Tenure Research Director at INSERM
@gguaschresearch.bsky.social
Epithelial stem Cell research, cancer, plasticity, transition zone, organoid models, microenvironment
I am very happy to share the release of our new collaborative manuscript uncovering a key and novel mechanism driving cancer progression at one of the most sensitive sites of transformation — the anorectal junction, the transition area between the anus and rectum. Cell Reports by Cell Press
Injury and inflammation promote cancer progression at the anorectal junction
Petitpas et al. dissect the single-cell transcriptome underlying the sequential steps
of pre-malignant lesions and early anorectal cancer, mimicking disease evolution seen
in patients, at the epitheli...
www.cell.com
November 19, 2025 at 9:22 AM
I am very happy to share the release of our new collaborative manuscript uncovering a key and novel mechanism driving cancer progression at one of the most sensitive sites of transformation — the anorectal junction, the transition area between the anus and rectum. Cell Reports by Cell Press