George Galea
georgegalea.bsky.social
George Galea
@georgegalea.bsky.social
Researcher in Pepperkok team @EMBL, Heidelberg. All about big data, high-throughput screening, Golgi DNA damage response & endomembrane-nuclear communication
We’re kicking off the year with a new preprint update! Discover how DNA repair proteins coordinate between the Golgi and nucleus. Our latest data reveal how ATM, NBN, and GMAP210 regulate RAD51C localization to drive HR repair.

Thanks to @kuodyte.bsky.social & Pepperkok team @embl.org
Spatiotemporal dynamics of RAD51C between the Golgi and nucleus regulates homologous recombination and genomic stability.
Intra-organelle communication is essential for cellular homeostasis, but the coordination between nuclear processes and cytoplasmic compartments remains poorly understood. Here, we uncover a novel spa...
www.biorxiv.org
January 9, 2025 at 6:39 PM
Thrilled to be part of the project showing how Dextromethorphan, an over-the-counter cough syrup, modulates membrane trafficking to mitigate lung fibrosis.

Full paper: www.science.org/doi/10.1126/...

Non-tech summary: www.eurekalert.org/news-release...
December 19, 2024 at 12:32 PM