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This publication in Nature was fascinating: Cancer cells swap mutated mitochondria with tumor-infiltrating immune cells (TILs). Metabolism is the keystone of cancer immunotherapy, yet often overlooked. Could this mechanism provide clues to increasing patient response? www.nature.com/articles/s41...
Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature
Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.
www.nature.com
February 3, 2025 at 3:38 PM
This publication in Nature was fascinating: Cancer cells swap mutated mitochondria with tumor-infiltrating immune cells (TILs). Metabolism is the keystone of cancer immunotherapy, yet often overlooked. Could this mechanism provide clues to increasing patient response? www.nature.com/articles/s41...