Genome Data Science
@genomedatalab.bsky.social
Computational biology @UCPH_Research/@IRBBarcelona: genetics & evolution of tumors & human populations. #ERC, #HorizonEU, #NNF, #DCS, #DFF funded. PI @fransupek.bsky.social Our webpage https://www.genomedatalab.org/
🧬Indels drive the separation into m-SBS3a & SBS3b HRd signatures
Only SBS3b strongly predicts survival in ovarian cancer patients, exceeding other genetic markers
➕utility of MMRd signatures also improved with indel+SNV joint inference
Read more: 👇
genomemedicine.biomedcentral.com/articles/10....
Only SBS3b strongly predicts survival in ovarian cancer patients, exceeding other genetic markers
➕utility of MMRd signatures also improved with indel+SNV joint inference
Read more: 👇
genomemedicine.biomedcentral.com/articles/10....
Joint inference of mutational signatures from indels and single-nucleotide substitutions reveals prognostic impact of DNA repair deficiencies - Genome Medicine
Background Mutational signatures are increasingly used to understand the mechanisms causing cancer. However, their important applications in predicting prognosis and stratifying patients for therapy a...
genomemedicine.biomedcentral.com
July 3, 2025 at 1:56 PM
🧬Indels drive the separation into m-SBS3a & SBS3b HRd signatures
Only SBS3b strongly predicts survival in ovarian cancer patients, exceeding other genetic markers
➕utility of MMRd signatures also improved with indel+SNV joint inference
Read more: 👇
genomemedicine.biomedcentral.com/articles/10....
Only SBS3b strongly predicts survival in ovarian cancer patients, exceeding other genetic markers
➕utility of MMRd signatures also improved with indel+SNV joint inference
Read more: 👇
genomemedicine.biomedcentral.com/articles/10....