Gencode Genes
@gencodegenes.bsky.social
Human And Vertebrate Analysis aNd Annotation (HAVANA) team, part of the Ensembl group at the European Bioinformatics Institute.
These new transcripts all have a CDS that is based upon the MANE_Select transcript for the gene, but have unique splicing either within their UTRs or between internal coding exons. Each of these unique splice sites has passed our stringent QC filters to ensure their accuracy.
September 3, 2025 at 11:16 AM
These new transcripts all have a CDS that is based upon the MANE_Select transcript for the gene, but have unique splicing either within their UTRs or between internal coding exons. Each of these unique splice sites has passed our stringent QC filters to ensure their accuracy.
This release sees the addition of >121000 new full-length human protein-coding transcripts based on long-read RNA-seq data that have been integrated into GENCODE using the TAGENE annotation pipeline.
September 3, 2025 at 11:16 AM
This release sees the addition of >121000 new full-length human protein-coding transcripts based on long-read RNA-seq data that have been integrated into GENCODE using the TAGENE annotation pipeline.
The GENCODE Primary dataset is now displayed by default for human and mouse in @ensembl.bsky.social. More information about how this set is created is available here: www.gencodegenes.org/pages/gencod... and details on how to change the default display settings here: www.ensembl.info/2025/04/29/d...
GENCODE - The GENCODE Primary transcript set
www.gencodegenes.org
May 8, 2025 at 9:13 AM
The GENCODE Primary dataset is now displayed by default for human and mouse in @ensembl.bsky.social. More information about how this set is created is available here: www.gencodegenes.org/pages/gencod... and details on how to change the default display settings here: www.ensembl.info/2025/04/29/d...
Can also confirm that intron in 3' UTR does not exclude from MANE consideration - see e.g. BSN (www.ensembl.org/Homo_sapiens...) but for such cases we require evidence of NMD avoidance/functional product in the event of NMD. 2/2
Gene: BSN (ENSG00000164061) - Summary - Homo_sapiens - Ensembl genome browser 113
www.ensembl.org
December 11, 2024 at 2:13 PM
Can also confirm that intron in 3' UTR does not exclude from MANE consideration - see e.g. BSN (www.ensembl.org/Homo_sapiens...) but for such cases we require evidence of NMD avoidance/functional product in the event of NMD. 2/2
@nickywhiffin.bsky.social - HAVANA group here - sorry no reference comes immediately to mind. But we'll do some digging as its a good question! As @iansudbery.bsky.social says, assumption has been that introns in UTR are no different to introns in CDS. 1/2
December 11, 2024 at 2:13 PM
@nickywhiffin.bsky.social - HAVANA group here - sorry no reference comes immediately to mind. But we'll do some digging as its a good question! As @iansudbery.bsky.social says, assumption has been that introns in UTR are no different to introns in CDS. 1/2