George O'Toole (he/him/his)
@geiselbiofilm.bsky.social
Elmer R. Pfefferkorn, PhD, Professor of Microbiology & Immunology at the Geisel School of Medicine, EiC of the Journal of Bacteriology; Bacterial Biofilms, Surface Sensing, c-di-GMP Signaling, Polymicrobial Communities & Gut Microbiota in Cystic Fibrosis
JB Editor's Choice: Panich, Wadhwa et al. describe a new type of motility in Salmonella they refer to as "swashing", which does not appear to require active propulsion.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
December 1, 2025 at 1:23 PM
JB Editor's Choice: Panich, Wadhwa et al. describe a new type of motility in Salmonella they refer to as "swashing", which does not appear to require active propulsion.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
Reposted by George O'Toole (he/him/his)
100 Literature terms from a pubmed search of Biofilm from the last three years @ukbiofilms.bsky.social
November 21, 2025 at 5:54 PM
100 Literature terms from a pubmed search of Biofilm from the last three years @ukbiofilms.bsky.social
Reposted by George O'Toole (he/him/his)
🎉 #JVirology is pleased to announce the selectees for our inaugural New Voices in Virology collection! Chosen from 275+ applicants, these early-career scientists stood out for their creative proposals & strong career trajectories. ➡️ Meet the New Voices: asm.social/2HY
November 26, 2025 at 2:19 PM
🎉 #JVirology is pleased to announce the selectees for our inaugural New Voices in Virology collection! Chosen from 275+ applicants, these early-career scientists stood out for their creative proposals & strong career trajectories. ➡️ Meet the New Voices: asm.social/2HY
JB Editor's Choice: Endres, Lehman et al. use a cool genetic selection to help identify 4 different pyruvate transporters in S. aureus, indicating the importance of this substrate for this microbe.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
November 26, 2025 at 1:47 PM
JB Editor's Choice: Endres, Lehman et al. use a cool genetic selection to help identify 4 different pyruvate transporters in S. aureus, indicating the importance of this substrate for this microbe.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
Reposted by George O'Toole (he/him/his)
November 25, 2025 at 3:47 PM
JB Editor's Choice: Laurie Comstock discusses the history of model gut Bacteroidales (B. frag and B. theta) - bugs of increasing importance in our study of the gut microbiota and system-wide impacts of gut microbes.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
November 25, 2025 at 3:31 PM
JB Editor's Choice: Laurie Comstock discusses the history of model gut Bacteroidales (B. frag and B. theta) - bugs of increasing importance in our study of the gut microbiota and system-wide impacts of gut microbes.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
Reposted by George O'Toole (he/him/his)
Join us on Dec. 8 from 12-1 p.m. ET for a conversation with Nobel Laureate Dr. Katalin Karikó, where she’ll share insights from her memoir "Breaking Through: My Life in Science"—a story of resilience, discovery and revolutionizing medicine. Register now: asm.social/2HH
November 24, 2025 at 5:35 PM
Join us on Dec. 8 from 12-1 p.m. ET for a conversation with Nobel Laureate Dr. Katalin Karikó, where she’ll share insights from her memoir "Breaking Through: My Life in Science"—a story of resilience, discovery and revolutionizing medicine. Register now: asm.social/2HH
Reposted by George O'Toole (he/him/his)
Mark your calendars — Giving Tuesday is ONE week away!
On Giving Tuesday, your support helps power the discoveries, courses, and life-changing experiences that start at the Marine Biological Laboratory.
Give early: https://www.mbl.edu/give
#GivingTuesday #ScienceStartsHere #MBL
On Giving Tuesday, your support helps power the discoveries, courses, and life-changing experiences that start at the Marine Biological Laboratory.
Give early: https://www.mbl.edu/give
#GivingTuesday #ScienceStartsHere #MBL
November 25, 2025 at 1:52 PM
Mark your calendars — Giving Tuesday is ONE week away!
On Giving Tuesday, your support helps power the discoveries, courses, and life-changing experiences that start at the Marine Biological Laboratory.
Give early: https://www.mbl.edu/give
#GivingTuesday #ScienceStartsHere #MBL
On Giving Tuesday, your support helps power the discoveries, courses, and life-changing experiences that start at the Marine Biological Laboratory.
Give early: https://www.mbl.edu/give
#GivingTuesday #ScienceStartsHere #MBL
JB Editor's Choice: Bourret and colleagues update our understanding of the pseudo-receiver domains, nicely setting the stage for future work on these domains.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
November 24, 2025 at 3:15 PM
JB Editor's Choice: Bourret and colleagues update our understanding of the pseudo-receiver domains, nicely setting the stage for future work on these domains.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
Reposted by George O'Toole (he/him/his)
Early abstracts for the ASM Health Meeting close Dec. 2.
Diagnostics, vaccines, therapeutics, clinical ID, public health & more.
👉 asm.social/2HD
Diagnostics, vaccines, therapeutics, clinical ID, public health & more.
👉 asm.social/2HD
November 24, 2025 at 2:20 PM
Early abstracts for the ASM Health Meeting close Dec. 2.
Diagnostics, vaccines, therapeutics, clinical ID, public health & more.
👉 asm.social/2HD
Diagnostics, vaccines, therapeutics, clinical ID, public health & more.
👉 asm.social/2HD
Reposted by George O'Toole (he/him/his)
The diagnostic landscape for respiratory viruses has evolved dramatically, with widespread institution of molecular tests both in laboratories of all sizes, but also at the point of care – and even consumer direct testing. What’s next for respiratory virus testing? asm.org/podcasts/edi...
November 21, 2025 at 11:34 PM
The diagnostic landscape for respiratory viruses has evolved dramatically, with widespread institution of molecular tests both in laboratories of all sizes, but also at the point of care – and even consumer direct testing. What’s next for respiratory virus testing? asm.org/podcasts/edi...
The newest issue of JB is out! This month's issue has article on topics including bacterial pseudo-receiver domains, B. frag/B.theta as model bugs, peptidoglycomics, pyruvate transport in Staph, "swashing" motility, and more! Check it out!
journals.asm.org/toc/jb/207/11
journals.asm.org/toc/jb/207/11
November 21, 2025 at 4:36 PM
The newest issue of JB is out! This month's issue has article on topics including bacterial pseudo-receiver domains, B. frag/B.theta as model bugs, peptidoglycomics, pyruvate transport in Staph, "swashing" motility, and more! Check it out!
journals.asm.org/toc/jb/207/11
journals.asm.org/toc/jb/207/11
Excited to share new work from Sarvesh Surve examining the gut microbiota of adults with CF using colonoscopy samples and a culturomics approach. We note continued depletion of Bacteroidota (which we noted in kids) & enrichment of aerobes in the mucosa of pwCF.
pubmed.ncbi.nlm.nih.gov/41256617/
pubmed.ncbi.nlm.nih.gov/41256617/
November 21, 2025 at 3:09 PM
Excited to share new work from Sarvesh Surve examining the gut microbiota of adults with CF using colonoscopy samples and a culturomics approach. We note continued depletion of Bacteroidota (which we noted in kids) & enrichment of aerobes in the mucosa of pwCF.
pubmed.ncbi.nlm.nih.gov/41256617/
pubmed.ncbi.nlm.nih.gov/41256617/
Reposted by George O'Toole (he/him/his)
The global burden of pulmonary disease caused by Mycobacterium avium complex (MAC-PD) is increasing. This #JClinMicro article presents clinical scenarios in which MAC-PD recurrence may occur and examines genotyping techniques for responding to them. asm.social/2GY
November 19, 2025 at 4:25 PM
The global burden of pulmonary disease caused by Mycobacterium avium complex (MAC-PD) is increasing. This #JClinMicro article presents clinical scenarios in which MAC-PD recurrence may occur and examines genotyping techniques for responding to them. asm.social/2GY
New in JB: Zhao, You et al. use an Argonaute-based system that functions at physiological temperatures to edit the genome of Mycobacterium smegmatis.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
November 19, 2025 at 4:28 PM
New in JB: Zhao, You et al. use an Argonaute-based system that functions at physiological temperatures to edit the genome of Mycobacterium smegmatis.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
Reposted by George O'Toole (he/him/his)
🧫It’s #BiofilmWeek 2025!
✨ Head over to our LinkedIn and Instagram for new content released throughout the week - showcasing the science and innovation driving the biofilm community.
💬 LinkedIn tinyurl.com/3xx2b2dy
💬 Instagram instagram.com/ukbiofilms
👉 biofilms.ac.uk/biofilmweek #WAAW #MicroSky
✨ Head over to our LinkedIn and Instagram for new content released throughout the week - showcasing the science and innovation driving the biofilm community.
💬 LinkedIn tinyurl.com/3xx2b2dy
💬 Instagram instagram.com/ukbiofilms
👉 biofilms.ac.uk/biofilmweek #WAAW #MicroSky
November 18, 2025 at 9:22 AM
🧫It’s #BiofilmWeek 2025!
✨ Head over to our LinkedIn and Instagram for new content released throughout the week - showcasing the science and innovation driving the biofilm community.
💬 LinkedIn tinyurl.com/3xx2b2dy
💬 Instagram instagram.com/ukbiofilms
👉 biofilms.ac.uk/biofilmweek #WAAW #MicroSky
✨ Head over to our LinkedIn and Instagram for new content released throughout the week - showcasing the science and innovation driving the biofilm community.
💬 LinkedIn tinyurl.com/3xx2b2dy
💬 Instagram instagram.com/ukbiofilms
👉 biofilms.ac.uk/biofilmweek #WAAW #MicroSky
Pls share: HHMI - Program Officer - Science Education Alliance
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
Program Officer - Science Education Alliance
Primary Work Address: 4000 Jones Bridge Road, Chevy Chase, MD, 20815 Current HHMI Employees, click here to apply via your Workday account. HHMI is focused on supporting and moving science forward in a...
hhmi.wd1.myworkdayjobs.com
November 18, 2025 at 1:11 PM
Pls share: HHMI - Program Officer - Science Education Alliance
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
Reposted by George O'Toole (he/him/his)
Microbiologists make their mark in many fields. Those interested in pivoting from bench research must strategically network, gain necessary skills and translate lab skills to any sector. Learn more about how to navigate a job change or career transition. asm.org/articles/202...
Pivoting From Research to Other Microbial Science Careers | ASM.org
The microbial sciences intersects with many disciplines. Those interested in pivoting from bench research must strategically network, gain necessary skills and translate lab skills to any sector.
asm.org
November 17, 2025 at 12:31 PM
Microbiologists make their mark in many fields. Those interested in pivoting from bench research must strategically network, gain necessary skills and translate lab skills to any sector. Learn more about how to navigate a job change or career transition. asm.org/articles/202...
New in JB: Shen, Tse-Dinh et al. explore the role of a DNA topoisomerase I in the physiology of the important intracellular pathogen Chlamydia trachomatis.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
November 17, 2025 at 2:39 PM
New in JB: Shen, Tse-Dinh et al. explore the role of a DNA topoisomerase I in the physiology of the important intracellular pathogen Chlamydia trachomatis.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
Reposted by George O'Toole (he/him/his)
November 16, 2025 at 10:15 PM
Reposted by George O'Toole (he/him/his)
‘The latest surveillance data found that the number of antibiotic-resistant infections in 2024 equated to an average of nearly 400 newly reported cases a week.’
www.theguardian.com/society/2025...
www.theguardian.com/society/2025...
Deaths linked to antibiotic-resistant superbugs rose 17% in England in 2024
Data also shows an average of nearly 400 newly reported cases of antibiotic-resistant infections a week last year
www.theguardian.com
November 13, 2025 at 11:27 PM
‘The latest surveillance data found that the number of antibiotic-resistant infections in 2024 equated to an average of nearly 400 newly reported cases a week.’
www.theguardian.com/society/2025...
www.theguardian.com/society/2025...
New in JB: da Silva Rocha, Berrêdo-Pinho et al. explore the role of protein prenylation inhibition on Mycobacterium leprae pathogenesis versus macrophages, and propose new therapeutic strategies based on these findings.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
November 14, 2025 at 4:34 PM
New in JB: da Silva Rocha, Berrêdo-Pinho et al. explore the role of protein prenylation inhibition on Mycobacterium leprae pathogenesis versus macrophages, and propose new therapeutic strategies based on these findings.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
Reposted by George O'Toole (he/him/his)
Pleased to share our review on S-layers with @bupbuse.bsky.social, Andriko von Kügelgen, and @tbharat-lab.bsky.social, where we explore recent advances and argue that deeper insight into S-layers is key to deciphering microbial interactions and community organization. @mpi-bio-fml.bsky.social
Assembly, architecture and functional roles of microbial surface layers
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Assembly, architecture and functional roles of microbial surface layers - Nature Reviews Microbiology
Surface layers (S-layers) are ubiquitous protein assemblies that coat prokaryotic cells, with their functional roles increasingly coming into focus. In this Review, Isbilir and colleagues discuss rece...
www.nature.com
November 13, 2025 at 9:16 PM
Pleased to share our review on S-layers with @bupbuse.bsky.social, Andriko von Kügelgen, and @tbharat-lab.bsky.social, where we explore recent advances and argue that deeper insight into S-layers is key to deciphering microbial interactions and community organization. @mpi-bio-fml.bsky.social
A really nice profile of Fabrice Jean-Pierre, a former postdoc in the lab doing great work in his own lab at the University of Sherbrooke. Congrats Fabrice!
cysticfibrosis.ca/blog/dr.-fab...
cysticfibrosis.ca/blog/dr.-fab...
Dr. Fabrice Jean-Pierre: Uncovering the Invisible Battles in CF Lungs
Dr. Fabrice Jean-Pierre’s research digs into a problem many people with cystic fibrosis (CF) know intimately: chronic lung infections. Even as treatments like Trikafta improve lung function and overal...
cysticfibrosis.ca
November 14, 2025 at 1:50 AM
A really nice profile of Fabrice Jean-Pierre, a former postdoc in the lab doing great work in his own lab at the University of Sherbrooke. Congrats Fabrice!
cysticfibrosis.ca/blog/dr.-fab...
cysticfibrosis.ca/blog/dr.-fab...
Reposted by George O'Toole (he/him/his)
How does Streptococcus pneumoniae (Spn) manipulate host metabolism to promote its survival? In #mBio, researchers reveal a novel strategy whereby Spn-derived hydrogen peroxide disrupts the host TCA cycle, reprogramming metabolism in lung epithelial cells. asm.social/2Gx
November 13, 2025 at 3:52 PM
How does Streptococcus pneumoniae (Spn) manipulate host metabolism to promote its survival? In #mBio, researchers reveal a novel strategy whereby Spn-derived hydrogen peroxide disrupts the host TCA cycle, reprogramming metabolism in lung epithelial cells. asm.social/2Gx