Claret Bio SRSLY

Timeline: All updates coming Q3/Q4 this year, probably alongside the long-awaited 600-cycle 1.5B flowcells that Steve Barnard teased over a year ago. Hardware improvements finally catching up to promises.

DRAGEN v4.4: Onboard analysis getting updated but unclear if it's full version like standalone servers or stripped-down instrument version. Details TBD - hoping someone in the know can clarify.

Quality Improvements: Better Q-scores with less PhiX needed (1% new = 5% old). Likely algorithm tweaks reducing signal crosstalk. Means more robust sequencing for tricky low-complexity libraries plus overall quality gains.

Index-First Sequencing: New feature lets you check pooling quality before full sequencing starts. Sounds useful but creates a dilemma - what if it looks bad? Can't reuse reagents once you've started, so may only help well-funded cores.

Staggered Runs: NovaSeq X finally gets dual flowcell capability - no more 48hr waits while one side monopolizes the instrument. Game changer for high-throughput labs dealing with batching headaches when mixing different run types.

Right after having you round to the mothership?

For all their faults they've got tech support down cold.