Gary Schiltz
@garyeschiltz.bsky.social
Excitingly, our most promising new compound (P374) shows in vivo activity at reducing omentum colonization of ovarian cancer cells and significantly reduced tumor weights, tumor volumes, and the number of ovarian tumors.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Novel PROTACs targeting tissue transglutaminase (TG2) suppress tumorigenicity of ovarian cancer cells
Tissue transglutaminase (TG2), a multifunctional enzyme involved in protein crosslinking through transamidation, fibronectin–integrin interactions and…
www.sciencedirect.com
October 18, 2025 at 12:16 PM
Excitingly, our most promising new compound (P374) shows in vivo activity at reducing omentum colonization of ovarian cancer cells and significantly reduced tumor weights, tumor volumes, and the number of ovarian tumors.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...