Francesco Bertoni
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frbertoni.bsky.social
Francesco Bertoni
@frbertoni.bsky.social
98 followers 190 following 63 posts
Institute of Oncology Research. President, ICML Local Organizing Committee. USI. Personal opinions only. #lymsm #lymphoma
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frbertoni.bsky.social
-Novel thiosemicarbazones demonstrate pronounced anti-tumor activity in marginal zone lymphoma models, also overcoming resistance to targeted agents
doi.org/10.1158/1535...
Abstract B113: Novel thiosemicarbazones demonstrate pronounced anti-tumor activity in marginal zone lymphoma models, also overcoming resistance to targeted agents
AbstractBackground.. Despite significant advancements in anti-lymphoma therapies in recent years, treatment failure and disease relapse remain significant clinical challenges in B-cell lymphoma. There...
doi.org
October 25, 2025 at 10:59 AM
frbertoni.bsky.social
-CBP/EP300 inhibitor OPN-6602 in marginal zone lymphomas: preclinical activity as a single agent and in combination with BTK inhibition
doi.org/10.1158/1535...
Abstract C024: CBP/EP300 inhibitor OPN-6602 in marginal zone lymphomas: preclinical activity as a single agent and in combination with BTK inhibition
AbstractBackground.. Chromatin accessibility is frequently disrupted in cancer cells, often as a result of deregulated activity of histone-modifying enzymes. The genes encoding the acetyltransferases ...
doi.org
October 25, 2025 at 10:59 AM
frbertoni.bsky.social
-Development of isogenic models of marginal zone lymphoma for therapeutic target discovery in TET2-deficient disease
doi.org/10.1158/1535...
Abstract C023: Development of isogenic models of marginal zone lymphoma for therapeutic target discovery in TET2-deficient disease
AbstractIntroduction.. The family of ten-eleven translocation dioxygenases (TETs) regulates dioxygenase activity-dependent DNA demethylation and dioxygenase activity-independent histone modification, ...
doi.org
October 25, 2025 at 10:59 AM