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flo-dimeo.bsky.social
Flo Di Meo
@flo-dimeo.bsky.social
96 followers 200 following 4 posts
Computational chemist trying to understand drug membrane transporters in pharmacology as well as everything I don’t understand… Inserm Researcher - Limoges, France
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flo-dimeo.bsky.social
Veronica's work about structural dynamics of ABCB4 finally out in CSBJ @insermna.bsky.social @inserm.fr #ABCtransporter #MD #membprot #compchem www.sciencedirect.com/science/arti...
Membrane-dependent dynamics and dual translocation mechanisms of ABCB4: Insights from molecular dynamics simulations
ABCB4 is an ATP-binding cassette transporter expressed at the canalicular membrane of hepatocytes and responsible for translocating phosphatidylcholin…
www.sciencedirect.com
March 26, 2025 at 7:38 AM
flo-dimeo.bsky.social
Glad to share collaboration with Ali Makky about New porphysomes for improved photodynamic therapy applications in JCI @univparissaclay.bsky.social @insermna.bsky.social @cnrs.fr @inserm.fr www.sciencedirect.com/science/arti...
Next generation of porphysomes for improved photodynamic therapy applications
Porphysomes are a class of liposome-like nanoparticles that have demonstrated efficacy in photothermal therapy (PTT) and photodynamic therapy (PDT) ag…
www.sciencedirect.com
March 26, 2025 at 7:36 AM
Reposted by Flo Di Meo
abcmeeting.bsky.social
We had an amazing time with the ABC family and already miss you all! Can’t wait to hear your exciting talks, have great discussions, and hit the slopes of the Alps again. #ABC2025

See you next time!🗻⛷️🚠🧬🧫🧪💙
March 7, 2025 at 9:13 AM
flo-dimeo.bsky.social
Happy to share here our revised version of our study about membrane-dependent structural dynamics of ABCB4 membrane transporter. Huge work from Veronica @inserm.fr @insermna.bsky.social @unilim.bsky.social #ABCtransporter #MD doi.org/10.1101/2024...
Membrane-Dependent Dynamics and Dual Translocation Mechanisms of ABCB4: Insights from Molecular Dynamics Simulations
ABCB4 is an ATP-binding cassette transporter expressed at the canalicular membrane of hepatocytes and responsible for translocating phosphatidylcholine into bile. Despite the recent cryo-EM structures...
doi.org
March 3, 2025 at 7:26 AM
Reposted by Flo Di Meo
elenapapaleo.bsky.social
PhD Opportunity: AI-driven Protein Binder Design.
Join a cutting-edge DTU & Novo Nordisk collaboration! Work with AI, automation & protein engineering in a closed-loop design pipeline.
efzu.fa.em2.oraclecloud.com/hcmUI/Candid...
#PhD #AI #ProteinDesign #Bioinformatics #MachineLearning #Biology
PhD scholarship in AI Oracles for Fitness Landscape Optimization on Molecular Binders - DTU Health Tech
As part of a joint research collaboration between DTU and Novo Nordisk, we are looking for a Ph.D.-candidate to join our multidisciplinary research program focusing on the interplay between AI-based p...
efzu.fa.em2.oraclecloud.com
February 28, 2025 at 7:33 PM
flo-dimeo.bsky.social
Surprisingly, it sounds possible for a computational chemist to also play with membrane transporters, cells and organ-on-chips in pharmacology! It took time but it was fun, thanks to Nicolas, Quentin and Isy @inserm @unilim.bsky.social in Scientific Reports

rdcu.be/d6WJ6
Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics
Scientific Reports - Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics
www.nature.com
January 20, 2025 at 7:13 PM