Ethan Garner
fleshball.bsky.social
Ethan Garner
@fleshball.bsky.social
Microscopist, Biochemist, Master MC. Mostly a membrane full of water. (Also a Professor at Harvard MCB - studying how bacteria grow and divide)
Edit - Elife has the full publication here.
elifesciences.org/reviewed-pre...
The interplay of membrane tension and FtsZ filament condensation on the initiation and progression of cell division in B. subtilis
elifesciences.org
August 26, 2025 at 3:16 PM
2) we also see the constriction rate of the Z ring scales with the membrane tension, indicating ring constriction and septal synthesis occurs via a Brownian ratchet mechanism.
August 19, 2025 at 7:48 PM
5/ Finally, our measurements indicate that the vast majority (99.9%) of the turgor pressure is held back by the cell wall, and that the membrane only resists 0.1% of the internal pressure.
May 20, 2025 at 5:17 PM
4/ This points to a Brownian ratchet model for constriction, where membrane fluctuations at the tip of the septa create room for septal enzymes to insert new wall material, which then reinforces the inward fluctuation.
May 20, 2025 at 5:17 PM
3/ Surprisingly, they found that once division starts, the rate of septal constriction increases as membrane tension decreases, indicating that membrane fluctuations, rather than cell wall synthesis, are limiting for cell division.
May 20, 2025 at 5:17 PM
2/ By being able to modulate and measure tension, Diego and Lei found 1 that the condensation of FtsZ filaments (helped by FtsZ bundling proteins) works to overcome the membrane tension to bend it inward.
May 20, 2025 at 5:17 PM
October 9, 2024 at 7:56 PM
I can't believe I missed this. Congrats!
October 9, 2024 at 4:41 PM
@cellforganized.bsky.social, @goleylab.bsky.social ‬ - I'm new to bluesky, can you repost?
October 9, 2024 at 4:41 PM