Filippo Binci
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filbinci.bsky.social
Filippo Binci
@filbinci.bsky.social
Post-Doc at UniPD. Working on calcium signalling in plant development and plant-microbe interactions #PlantScience #MPMI
6/6) Overall, LjMLO4 is a key molecular hub between peptide signalling, Ca2+ transport and root system architecture, highlighting MLO integration of developmental, nutrition and symbiotic cues.

Thanks to my supervisors, collaborators and MSc students!

Feel free to get in touch for comments!
September 22, 2025 at 8:06 AM
5/6) Then, we tested mlo4 responsiveness to exogenous treatments with Lj RALF peptides. We found that mutants are less sensitive to LjRALF34 than WT in terms of root growth inhibition and Ca2+ signalling, supporting recent evidence of MLO as signal amplifiers of the RALF/CrRLK1L signalling
September 22, 2025 at 8:06 AM
4/6) Given the recently proposed role of MLO functioning as Ca2+ channel downstream of RALFs, first we tested that LjMLO4 can mobilize Ca2+ across biological membranes by heterologous expression in E. coli.
September 22, 2025 at 8:06 AM
3/6) Surprisingly, no major AM-related phenotypes were visible in mlo4 mutants, but we uncovered clear root developmental phenotypes irrespective of root colonization by AM fungi. mlo4 mutants have shorter and fewer lateral roots, and this is dependent on exogenous Ca2+ levels.
September 22, 2025 at 8:06 AM
2/6) We found that the promoter of LjMLO4 has a dual expression pattern in roots: strongly activated in arbusculated cells and a basal expression at lateral root primordia and root tips
September 22, 2025 at 8:06 AM
In the MSCA global fellowship there is a mandatory "outgoing phase", for mobility from the chosen european host to an "outgoing country" out of Europe and back.. EU bureaucratic language can be misleading :)
September 14, 2025 at 4:59 PM
I think both graphs gather applications for the chosen destination (in Europe or abroad). No data here about the country of origin of applicants, but only where they would like to go
September 14, 2025 at 4:14 PM