Have not tried and will not try. I don't even like having to use a very small amount of it on my pet's neck as an as-needed, monthly basis for my pet to prevent fleas & ear mites.

On the flip side of my previous comment, including older people on trials will also show which treatments help those who are in the phases of MS where there are less or no relapses but continuing progression of their disability.

It's good on multiple aspects that they are including older patients in trials now. Especially since the same DMTs may be safe for younger generations, however, they may have safety issues that come out in older people who have developed other health issues.

I 100% agree w/it. It has the potential. Just like too much acetaminophen can have dire consequences on liver, as well as other drugs on kidneys, etc. So if there's a risk of accumulation & there's data to back that up, why wouldn't we want to be careful in how much we use?