ferbyingvar.bsky.social
@ferbyingvar.bsky.social
Reposted
Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations. Read our work in ‪@natcardiovascres.nature.com by Marle Kraft et al.

rdcu.be/enhST
Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations
Nature Cardiovascular Research - Kraft et al. identify TIE2 activation as a key driver of PIK3CA-related venous malformations and demonstrate that inhibiting TIE2 signaling can suppress the growth...
rdcu.be
May 25, 2025 at 2:34 PM
Reposted
If you’re curious about why lymphatic endothelial cells have their jigsaw puzzle-like shape,
check out our paper
@Nature
rdcu.be/eejhZ
Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium
Nature - Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result...
rdcu.be
March 20, 2025 at 9:15 AM