Ferdous Nasri
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ferbsx.bsky.social
Ferdous Nasri
@ferbsx.bsky.social
42 followers 34 following 2 posts
Bioinformatician @HPI who likes people, traveling, dogs and programming ツ | codecurious co-founder | she/her
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Reposted by Ferdous Nasri
pascivers.bsky.social
Despite hundreds of published models for cancer drug response prediction, none are used in clinical practice.

Why?

In our preprint, we outline key challenges and introduce a living benchmark to help the field move forward.

Check out the thread by my co–first author @judith-bernett.bsky.social:
judith-bernett.bsky.social Judith Bernett @judith-bernett.bsky.social · Jun 3
🧬🖥️So excited to show you the outcome of @pascivers.bsky.social and my latest project: "From Hype to Health Check: Critical Evaluation of Drug Response Prediction Models with DrEval" doi.org/10.1101/2025.05.26.655288, published with M. Picciani, M. Wilhelm, K. Baum & @itisalist.bsky.social.
🧵1/10
Overview of the DrEval framework. Via input options, implemented state-of-the-art models can be compared against baselines of varying complexity. We address obstacles to progress in the field at each point in our pipeline: Our framework is available on PyPI and nf-core and we follow FAIReR standards for optimal reproducibility. DrEval is easily extendable as demonstrated here with a pseudocode implementation of a proteomics-based random forest. Custom viability data can be preprocessed with CurveCurator, leading to more consistent data and metrics. DrEval supports five widely used datasets with application-aware train/test splits that enable detecting weak generalization. Models are free to use provided or custom cell line– and drug features. The pipeline supports randomization-based ablation studies and performs robust hyperparameter tuning for all models. Evaluation is conducted using meaningful, bias-resistant metrics to avoid inflated results from artifacts such as Simpson’s paradox. All results are compiled into an interactive HTML report. Created in https://BioRender.com.
June 3, 2025 at 2:58 PM
ferbsx.bsky.social
Such a fun run!

Thanks to @hpi.bsky.social for making it possible 🎉
renardlab.bsky.social Renard Lab @renardlab.bsky.social · May 30
What a run! 🏃‍♀️🏃‍♂️
Last week, our group took part in the Berlin #Firmenlauf, and we had an amazing time out there, running, cheering each other on, and just enjoying the energy of the event! #TeamVibes

Thanks to everyone who made it such a memorable day 🤗 #ScienceInSneakers @hpi.bsky.social
@y.hartmar
May 30, 2025 at 9:44 AM
Reposted by Ferdous Nasri
renardlab.bsky.social
Ferdous Nasri presenting her work on the 'Spatio-temporal immunity index tool for infectious diseases' at the Digital Health Summit at University of Cape Town in South Africa!
Ferdous smiling in front of her poster.
February 7, 2025 at 4:33 PM
ferbsx.bsky.social
Happy that I had the honour of presenting my work at the Digital Health Summit in Cape Town, and got the chance to get into great discussions with researchers on the continent!

Thanks to Prof. Melissa Densmore for organising the summit and bringing us all together 💐
Ferdous presenting a poster on her research on "Saptio-temporal immunity index tool for infectious diseases" Group photo of the Digital Health Summit attendees at the University of Cape Town in South Africa.
February 7, 2025 at 4:29 PM