Francesco Dal Grande
fdalgrande.bsky.social
Francesco Dal Grande
@fdalgrande.bsky.social
Reposted by Francesco Dal Grande
Ever wondered about the funny moss growing on trees? Chances were good that you were looking at #lichen! These hybrid fungal-algae/cyanobacterial colonies are biosynthetically surprisingly diverse, as we show in our newest publication led by @garimasingh-gs.bsky.social doi.org/10.1099/mgen... (1/5)
Paired-omics-based exploration and characterization of biosynthetic diversity in lichenized fungi
The increasing demand for novel drug leads requires bioprospecting non-model taxa. Comparative genomics and correlative omics are a fast and efficient method for linking bioactive but genetically orph...
doi.org
December 18, 2025 at 8:58 AM
Reposted by Francesco Dal Grande
Are #lichens truly a treasure chest of #naturalproducts compared to non-lichenized #fungi? We put this to test using #BGC count as a proxy across ~400 #genomes.

Spoiler alert: They absolutely are!

#PKSs
#secondaryMetabolites
#Lecanoromycetes
#fungalGenomics

Article link: tinyurl.com/ynph7npe
February 28, 2025 at 2:30 PM
Reposted by Francesco Dal Grande
I enjoyed teaming with Garima, Francesco and Marnix to write this piece for @newphyt.bsky.social ...

Breaking into nature's secret medicine cabinet: lichens – a biochemical goldmine ready for discovery
nph.onlinelibrary.wiley.com/doi/abs/10.1...
February 27, 2025 at 3:34 PM