We used de novo assembly to reconstruct over 100 complete clinical genomes that preserved their , a leading edge hybrid ab initio annotation tool to annotate the genomes which discovered tens of novel genes, some of which are involved in antibiotic resistance, virulence, and host immune evasion.

Very proud of Ashley Swing, Monica Espinosa, Afif Elghraoui, and Sam Modlin for the work that we just published on the network-connectivity analysis of the tuberculosis Graph Pangenome. We report hidden mechanisms of resistance and host immune evasion.