Erin Sauve
@erinsauve.bsky.social
PhD candidate working on vivax malaria and drug resistance at @itmmalaria.bsky.social 🦠🦟🔬 | Returned PeaceCorps Volunteer - Madagascar 🇲🇬
Dr. Katherine Jessica Torres Fajardo ended Session 6 with a turbo talk on the antibody signatures of P. vivax infections from the Peruvian Amazon
February 13, 2025 at 9:12 AM
Dr. Katherine Jessica Torres Fajardo ended Session 6 with a turbo talk on the antibody signatures of P. vivax infections from the Peruvian Amazon
Dr. Steven Kho gave a captivating presentation in Session 6 on the splenic biomass in acute clinical Pv cases. No spleen leads to more circulating parasites and lower total biomass. And quantified in patients with a spleen around 88% biomass resides in the spleen and only 12% in circulation!
February 13, 2025 at 9:12 AM
Dr. Steven Kho gave a captivating presentation in Session 6 on the splenic biomass in acute clinical Pv cases. No spleen leads to more circulating parasites and lower total biomass. And quantified in patients with a spleen around 88% biomass resides in the spleen and only 12% in circulation!
Léa Baldor closed the session with PvDBP gene amplification and how this can be a protection mechanism against naturally acquired anti-PvDBP immunity.
February 13, 2025 at 6:45 AM
Léa Baldor closed the session with PvDBP gene amplification and how this can be a protection mechanism against naturally acquired anti-PvDBP immunity.
Dr. Maisa Araujo shared how transmission blocking is possible using atovaquone treated sugar feed in Anopheles darlingi females infected with P. vivax.
February 13, 2025 at 6:45 AM
Dr. Maisa Araujo shared how transmission blocking is possible using atovaquone treated sugar feed in Anopheles darlingi females infected with P. vivax.
#ICPVR2025 Session 5 ended with 3 amazing turbo talks! Sophia DonVito from Moon lab (robmoon.bsky.social) showed insights gained from using Pk transgenes to investigate the role of PvDBP and RBP2b in invasion.
February 13, 2025 at 6:45 AM
#ICPVR2025 Session 5 ended with 3 amazing turbo talks! Sophia DonVito from Moon lab (robmoon.bsky.social) showed insights gained from using Pk transgenes to investigate the role of PvDBP and RBP2b in invasion.
Dr. Carmen Fernandez-Becerra shares her work on cryptic P. vivax infections and extracellular vesicles as intracellulair communicators, with some beautiful images and single-cell spleen fibroblast data! EVs have great potential for novel biomarker discovery as well!
February 13, 2025 at 5:51 AM
Dr. Carmen Fernandez-Becerra shares her work on cryptic P. vivax infections and extracellular vesicles as intracellulair communicators, with some beautiful images and single-cell spleen fibroblast data! EVs have great potential for novel biomarker discovery as well!
Next, Dr. Vaneeta Singh presented on the prevalence of molecular markers in P. vivax in India. For the putative drug resistance markers, pvmdr1 was predominantly the MLL triple mutant and all pvcrt was wildtype.
February 13, 2025 at 5:51 AM
Next, Dr. Vaneeta Singh presented on the prevalence of molecular markers in P. vivax in India. For the putative drug resistance markers, pvmdr1 was predominantly the MLL triple mutant and all pvcrt was wildtype.
Day 2 of #ICPVR2025. Session 5 begins with Dr. Manoj Duraisingh noting we have some good invasion candidates already, but that the genome tells us there are more! The combination of Pk & Pc models to study Pv antigen inhibition and gene essentiality can be used to identify and test new candidates.
February 13, 2025 at 5:51 AM
Day 2 of #ICPVR2025. Session 5 begins with Dr. Manoj Duraisingh noting we have some good invasion candidates already, but that the genome tells us there are more! The combination of Pk & Pc models to study Pv antigen inhibition and gene essentiality can be used to identify and test new candidates.
Finally, our own Dalia Diaz-Delgado (daliia193.bsky.social) gave a fantastic turbo talk on a new set of P. knowlesi biomarkers from a Pk time course and compared Pk and Pv gene expression. (4/4)
February 12, 2025 at 8:26 PM
Finally, our own Dalia Diaz-Delgado (daliia193.bsky.social) gave a fantastic turbo talk on a new set of P. knowlesi biomarkers from a Pk time course and compared Pk and Pv gene expression. (4/4)
Dr. Usheer Kanjee used CRISPR/Cas9 knockouts and RNAi knockdowns to characterize the functional role of Band3 in invasion. (3/4)
February 12, 2025 at 8:26 PM
Dr. Usheer Kanjee used CRISPR/Cas9 knockouts and RNAi knockdowns to characterize the functional role of Band3 in invasion. (3/4)
Dr. Maria Ome Kaius shared the exciting advances and safety/feasibility of a point-of-care G6PD deficiency testing which is part of a revised case management package! (2/4)
February 12, 2025 at 8:26 PM
Dr. Maria Ome Kaius shared the exciting advances and safety/feasibility of a point-of-care G6PD deficiency testing which is part of a revised case management package! (2/4)
For #ICPVR2025 Day 1 Session 4, Kamala Thriemer (@kthriemer.bsky.social) presented the EFFORT study and the latest results showing 7 days of high-dose primaquine or tafenoquine have better antirelapse effectiveness than low-dose primaquine for 14 days! (1/4)
February 12, 2025 at 8:26 PM
For #ICPVR2025 Day 1 Session 4, Kamala Thriemer (@kthriemer.bsky.social) presented the EFFORT study and the latest results showing 7 days of high-dose primaquine or tafenoquine have better antirelapse effectiveness than low-dose primaquine for 14 days! (1/4)
Next, Dr. Anup Anvikar addressed the challenges and opportunities of radical cure of P. vivax in India. (4/4)
February 12, 2025 at 7:46 PM
Next, Dr. Anup Anvikar addressed the challenges and opportunities of radical cure of P. vivax in India. (4/4)
Perhaps something targeting the pre-erythrocytic stages! Dr. John Adams shared the importance of optimizing assays for P. vivax (I couldn’t agree more!) and the impressive implementation of optimized assays used to characterize pre-erythrocytic vaccine candidates. (3/4)
February 12, 2025 at 7:46 PM
Perhaps something targeting the pre-erythrocytic stages! Dr. John Adams shared the importance of optimizing assays for P. vivax (I couldn’t agree more!) and the impressive implementation of optimized assays used to characterize pre-erythrocytic vaccine candidates. (3/4)
Dr. Chetan Chitnis presented how the covid delay actually helped develop a potential DBP erythrocytic vaccine regimen since the delayed regimen was the most effective in reducing parasite multiplication rate…. Although the thought was raised, what about combining DBP with another target? (2/4)
February 12, 2025 at 7:46 PM
Dr. Chetan Chitnis presented how the covid delay actually helped develop a potential DBP erythrocytic vaccine regimen since the delayed regimen was the most effective in reducing parasite multiplication rate…. Although the thought was raised, what about combining DBP with another target? (2/4)
Dr. Jean Popovici kicked off Session 3 on Day 1 of #ICPVR2025 by sharing the data from his detailed patient follow-up study to better understand relapses and the work towards finding biomarkers to predict them. It looks like erythropoiesis could be the answer! (1/4)
February 12, 2025 at 7:46 PM
Dr. Jean Popovici kicked off Session 3 on Day 1 of #ICPVR2025 by sharing the data from his detailed patient follow-up study to better understand relapses and the work towards finding biomarkers to predict them. It looks like erythropoiesis could be the answer! (1/4)
Dr. Cindy Chu wrapped up Session 2 with a lovely turbo talk showing that high doses of PQ might not be needed for elimination in low transmission settings. (3/3)
February 12, 2025 at 7:19 PM
Dr. Cindy Chu wrapped up Session 2 with a lovely turbo talk showing that high doses of PQ might not be needed for elimination in low transmission settings. (3/3)
Next, Prof. Leanne Robinson gave a talk on new approaches to target hidden reservoirs highlighting nextgen RDTs for better diagnostics and PvSeroTAT for its ability to detect the hypnozoites! (2/3)
February 12, 2025 at 7:19 PM
Next, Prof. Leanne Robinson gave a talk on new approaches to target hidden reservoirs highlighting nextgen RDTs for better diagnostics and PvSeroTAT for its ability to detect the hypnozoites! (2/3)
Session 2 on Day 1 of #ICPVR2025 started with Dr. Tanu Jain from India’s National Center for Vector-borne Disease Control sharing the advancements in the IHP platform for country-wide data and India’s plan for elimination by 2030. (1/3)
February 12, 2025 at 7:19 PM
Session 2 on Day 1 of #ICPVR2025 started with Dr. Tanu Jain from India’s National Center for Vector-borne Disease Control sharing the advancements in the IHP platform for country-wide data and India’s plan for elimination by 2030. (1/3)
Session 1 ended with Dr. Kevin Baird stressing the importance of the window through which we view research & the importance of parasite biomass. There are extravascular windows we can’t easily see, which can harbor significant parasite burden and we need new tools to see into these windows. (3/3)
February 12, 2025 at 9:44 AM
Session 1 ended with Dr. Kevin Baird stressing the importance of the window through which we view research & the importance of parasite biomass. There are extravascular windows we can’t easily see, which can harbor significant parasite burden and we need new tools to see into these windows. (3/3)
Day 1, Session 1 of #ICPVR2025 began with a talk by Dr. Nick White sharing why P. vivax research matters and sharing “hope for a future where vivax malaria is eliminated in more areas of the world”. (2/3)
February 12, 2025 at 9:44 AM
Day 1, Session 1 of #ICPVR2025 began with a talk by Dr. Nick White sharing why P. vivax research matters and sharing “hope for a future where vivax malaria is eliminated in more areas of the world”. (2/3)
Dr. Manju Rahu the Director of ICMR Vector Control Research Centre kicked off the #ICPVR2025 conference inaugural session by welcoming us and reminding us that it’s going to be a fruitful few days with some of the smartest minds in malaria research in the room. (1/3)
February 12, 2025 at 9:44 AM
Dr. Manju Rahu the Director of ICMR Vector Control Research Centre kicked off the #ICPVR2025 conference inaugural session by welcoming us and reminding us that it’s going to be a fruitful few days with some of the smartest minds in malaria research in the room. (1/3)
Getting ready for the ICPvR conference in Puducherry, India. Get ready to follow along if you love P. vivax malaria research!
February 12, 2025 at 3:29 AM
Getting ready for the ICPvR conference in Puducherry, India. Get ready to follow along if you love P. vivax malaria research!
A butterfly shaped shell and a blue sky found on the beach in Puducherry, India. 🐚🦋
Perfect for my first post on Bluesky!
Perfect for my first post on Bluesky!
February 11, 2025 at 11:21 AM
A butterfly shaped shell and a blue sky found on the beach in Puducherry, India. 🐚🦋
Perfect for my first post on Bluesky!
Perfect for my first post on Bluesky!